SCHEMBL31552437

SCHEMBL31552437

CC(C)c1cccc(C(C)C)c1-c1ccc2c(Nc3nccc4cc(-c5c(C(C)C)cccc5C(C)C)ccc34)nccc2c1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
JAK2 O60674 1/20 0.44
TYK2 P29597 1/20 0.44
WNT3A P56704 5/20 0.40
KRAS P01116 1/20 0.39
SOS1 Q07889 1/20 0.39
TNF P01375 4/20 0.36
EGFR P00533 1/20 0.36
PIK3CA P42336 1/20 0.36
PIK3CB P42338 1/20 0.36
PIK3CG P48736 1/20 0.36
MAP4K4 O95819 1/20 0.36
TARS1 P26639 1/20 0.35
PLG P00747 1/20 0.35
F12 P00748 1/20 0.35
F11 P03951 1/20 0.35
KLKB1 P03952 1/20 0.35
PRSS1 P07477 1/20 0.35
PRSS2 P07478 1/20 0.35
PRSS3 P35030 1/20 0.35
TTK P33981 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23066763 1.00 JAK2 (0.44) JAK2TYK2WNT3AKRASSOS1
SCHEMBL23040275 0.91 JAK2 (0.40) JAK2TYK2WNT3AKRASSOS1
SCHEMBL31609529 0.91 JAK2 (0.40) JAK2TYK2WNT3AKRASSOS1
SCHEMBL23751344 0.86 KRAS (0.40) JAK2TYK2WNT3AKRASSOS1
SCHEMBL23751341 0.82 MAP4K4 (0.56) MAP4K4TARS1PLGF12F11
SCHEMBL14451011 0.72 KRAS (0.47) KRASSOS1EGFRF12
SCHEMBL23084472 0.72 ADRA2A (0.32) PIK3CBPIK3CGMAP4K4
SCHEMBL31591554 0.71 PRKCZ (0.45) EGFRPIK3CAPIK3CBPIK3CG
SCHEMBL23751342 0.71 PRKCZ (0.45) EGFRPIK3CAPIK3CBPIK3CG
SCHEMBL19083038 0.70 GRM4 (0.35)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250120303-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2025-04-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250120303-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OSBP, OCIAD1, OCIAD2 JAK2 4821/4885TYK2 4177/4885WNT3A 1791/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.