Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDAH1 | O94760 | 1/20 | 0.53 |
| ▸ | CA12 | O43570 | 6/20 | 0.43 |
| ▸ | CA9 | Q16790 | 6/20 | 0.43 |
| ▸ | CA1 | P00915 | 5/20 | 0.43 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | APEX1 | P27695 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23616010 | 0.85 | KMT2A (0.49) | DDAH1CA1CA2TSHRALDH1A1 | |
| SCHEMBL24939792 | 0.79 | ALDH1A1 (0.43) | TP53TSHRALDH1A1KDM4EHPGD | |
| SCHEMBL23094941 | 0.79 | MGLL (0.56) | DDAH1ALDH1A1HPGDKMT2ATDP1 | |
| SCHEMBL24741300 | 0.77 | ALDH1A1 (0.50) | CA12CA9CA1CA2TSHR | |
| SCHEMBL22520702 | 0.77 | TP53 (0.43) | TP53ALDH1A1KDM4EHPGDMAPT | |
| SCHEMBL21515041 | 0.76 | HCAR2 (0.45) | CA12CA9CA1CA2TSHR | |
| SCHEMBL21766061 | 0.76 | NSD2 (0.68) | DDAH1PTGS1PTGS2ALDH1A1HPGD | |
| SCHEMBL21766270 | 0.74 | DDAH1 (0.44) | DDAH1TSHRPTGS1PTGS2ALDH1A1 | |
| SCHEMBL24595426 | 0.72 | CYP3A4 (0.37) | CA1CA2TSHRTDP1 | |
| SCHEMBL27655843 | 0.72 | TSHR (0.50) | DDAH1CA12CA9CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9944730-B2 | Polymers derived from norbornadiene and maleic anhydride and use thereof | PROMERUS, LLC (US) | 2018-04-17 | — | — | US | disclosed |
| US-20180044449-A1 | POLYMERS DERIVED FROM NORBORNADIENE AND MALEIC ANHYDRIDE AND USE THEREOF | PROMERUS, LLC (US) | 2018-02-15 | — | — | US | disclosed |
| US-9834627-B2 | Polymers derived from norbornadiene and maleic anhydride and use thereof | PROMERUS, LLC (US) | 2017-12-05 | — | — | US | disclosed |
| US-20170190810-A1 | POLYMERS DERIVED FROM NORBORNADIENE AND MALEIC ANHYDRIDE AND USE THEREOF | PROMERUS, LLC (US) | 2017-07-06 | — | — | US | disclosed |