Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | ESR1 | P03372 | 2/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.31 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.31 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.31 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.31 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.31 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24288663 | 0.77 | ALDH1A1 (0.36) | MAPTKMT2AALDH1A1CYP2C19HIF1A | |
| SCHEMBL22242761 | 0.73 | — | — | |
| SCHEMBL18935764 | 0.71 | ALDH1A1 (0.34) | MAPTKMT2AALDH1A1ALOX15ESR1 | |
| SCHEMBL21341273 | 0.71 | MAPT (0.40) | MAPTKMT2AALDH1A1ALOX15ESR1 | |
| SCHEMBL19798182 | 0.71 | CNR1 (0.32) | — | |
| SCHEMBL6743584 | 0.70 | — | — | |
| SCHEMBL23084933 | 0.70 | MAPT (0.39) | MAPTKMT2AALDH1A1ALOX15ESR1 | |
| SCHEMBL20936254 | 0.69 | MAPT (0.45) | MAPTKMT2AALDH1A1ALOX15ESR1 | |
| SCHEMBL18381166 | 0.69 | MEN1 (0.38) | MAPTKMT2AALDH1A1CYP3A4MAPK1 | |
| SCHEMBL9806389 | 0.69 | MAPT (0.54) | MAPTKMT2AALDH1A1ALOX15ESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10240001-B2 | O-hydroxy-functionalized diamines, polyimides, methods of making each, and methods of use | KING ABDULLAH UNIVERSITY OF SCIENCE AND TECHNOLOGY (SA) | 2019-03-26 | — | — | US | disclosed |
| US-20170190842-A1 | O-HYDROXY-FUNCTIONALIZED DIAMINES, POLYIMIDES, METHODS OF MAKING EACH, AND METHODS OF USE | KING ABDULLAH UNIVERSITY OF SCIENCE AND TECHNOLOGY (SA) | 2017-07-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170190842-A1 | O-HYDROXY-FUNCTIONALIZED DIAMINES, POLYIMIDES, METHODS OF MAKING EACH, AND METHODS OF USE | ALKBH3, AOC1, PAM | MAPT 3676/4885KMT2A 354/4885ALDH1A1 540/4885 |
| US-10240001-B2 | O-hydroxy-functionalized diamines, polyimides, methods of making each, and methods of use | ALKBH3, AOC1, PAM | MAPT 3676/4885KMT2A 354/4885ALDH1A1 540/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.