Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28236543 | 0.78 | CA2 (0.38) | CA2 | |
| SCHEMBL28299732 | 0.77 | CA2 (0.37) | CA2 | |
| SCHEMBL28326536 | 0.75 | CA2 (0.36) | CA2 | |
| SCHEMBL27523471 | 0.75 | — | — | |
| SCHEMBL12582053 | 0.75 | — | — | |
| SCHEMBL7875758 | 0.75 | — | — | |
| SCHEMBL9845808 | 0.73 | CA2 (0.42) | CA2 | |
| SCHEMBL14580471 | 0.73 | CA2 (0.30) | CA2 | |
| SCHEMBL11082917 | 0.69 | ALDH1A1 (0.41) | CA2 | |
| SCHEMBL3488526 | 0.68 | CA2 (0.41) | CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10975091-B2 | Pyridine derivative | ASTELLAS PHARMA INC. (JP) | 2021-04-13 | — | — | US | disclosed |
| US-20200055868-A1 | PYRIDINE DERIVATIVE | ASTELLAS PHARMA INC. (JP) | 2020-02-20 | — | — | US | disclosed |
| US-10421762-B2 | Pyridine derivative | ASTELLAS PHARMA INC. (JP) | 2019-09-24 | — | — | US | disclosed |
| US-10023583-B2 | Bicyclic pyridine compound | ASTELLAS PHARMA INC. (JP) | 2018-07-17 | — | — | US | disclosed |
| US-10005762-B2 | Pyridine derivatives | ASTELLAS PHARMA INC. (JP) | 2018-06-26 | — | — | US | disclosed |
| US-20180022755-A1 | BICYCLIC PYRIDINE COMPOUND | ASTELLAS PHARMA INC. (JP) | 2018-01-25 | — | — | US | disclosed |
| US-20170362209-A1 | PYRIDINE DERIVATIVES | ASTELLAS PHARMA INC. (JP) | 2017-12-21 | — | — | US | disclosed |
| US-20170190715-A1 | PYRIDINE DERIVATIVE | ASTELLAS PHARMA INC. (JP) | 2017-07-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10005762-B2 | Pyridine derivatives | LAP3, PREP, DNPEP | CA2 206/4885 |
| US-20200055868-A1 | PYRIDINE DERIVATIVE | LAP3, PREP, DNPEP | CA2 179/4885 |
| US-10975091-B2 | Pyridine derivative | LAP3, PREP, DNPEP | CA2 179/4885 |
| US-10023583-B2 | Bicyclic pyridine compound | LAP3, PREP, DNPEP | CA2 139/4885 |
| US-20170362209-A1 | PYRIDINE DERIVATIVES | LAP3, PREP, DNPEP | CA2 206/4885 |
| US-10421762-B2 | Pyridine derivative | LAP3, PREP, DNPEP | CA2 179/4885 |
| US-20170190715-A1 | PYRIDINE DERIVATIVE | LAP3, PREP, DNPEP | CA2 179/4885 |
| US-20180022755-A1 | BICYCLIC PYRIDINE COMPOUND | LAP3, PREP, DNPEP | CA2 139/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.