Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.62 |
| ▸ | HPGD | P15428 | 2/20 | 0.62 |
| ▸ | GRM4 | Q14833 | 5/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | GRM5 | P41594 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | THPO | P40225 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28850385 | 1.00 | ALDH1A1 (0.62) | ALDH1A1KDM4EHPGDGRM4MEN1 | |
| SCHEMBL28798157 | 0.84 | MEN1 (0.54) | ALDH1A1KDM4EHPGDGRM4MEN1 | |
| SCHEMBL12595126 | 0.82 | ALDH1A1 (0.49) | ALDH1A1KDM4EHPGDGRM4MEN1 | |
| SCHEMBL10123059 | 0.81 | GRM4 (0.56) | ALDH1A1KDM4EHPGDGRM4MEN1 | |
| SCHEMBL17972534 | 0.78 | ALDH1A1 (0.52) | ALDH1A1KDM4EHPGDGRM4MEN1 | |
| SCHEMBL10060647 | 0.78 | L3MBTL1 (0.61) | ALDH1A1KDM4EHPGDGRM4MEN1 | |
| SCHEMBL31484371 | 0.74 | HRH4 (0.58) | ALDH1A1KDM4EHPGDGRM4MEN1 | |
| SCHEMBL20815523 | 0.74 | PDE5A (0.46) | ALDH1A1KDM4EHPGDGRM4MEN1 | |
| SCHEMBL20815516 | 0.74 | CASP3 (0.47) | ALDH1A1KDM4EHPGDGRM4MEN1 | |
| SCHEMBL28773675 | 0.74 | HRH4 (0.58) | ALDH1A1KDM4EHPGDGRM4MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180009213-A1 | LITHOGRAPHIC PRINTING PLATES PRECURSORS COMPRISING A RADIATION SENSITIVE IMAGEABLE LAYER WITH A CROSSLINKED SURFACE | MYLAN GROUP (VN) | 2018-01-11 | — | — | US | disclosed |
| US-20170190168-A1 | LITHOGRAPHIC PRINTING PLATES PRECURSORS COMPRISING A RADIATION SENSITIVE IMAGEABLE LAYER WITH A CROSSLINKED SURFACE | MYLAN GROUP (VN) | 2017-07-06 | — | — | US | disclosed |