Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | GPR35 | Q9HC97 | 9/20 | 0.39 |
| ▸ | DAO | P14920 | 1/20 | 0.31 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.31 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.31 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.31 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.31 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.31 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.31 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.31 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28811794 | 0.74 | GPR35 (0.45) | TSHRGPR35DAO | |
| SCHEMBL623033 | 0.70 | TSHR (0.52) | TSHRGPR35DAOHDAC3HDAC4 | |
| SCHEMBL1498222 | 0.69 | GSK3B (0.44) | TSHRGPR35DAO | |
| SCHEMBL28196417 | 0.67 | TSHR (0.65) | TSHRGPR35HDAC8 | |
| Hydrochloric Acid SCHEMBL28459433 | 0.67 | GSK3B (0.43) | TSHRGPR35DAO | |
| SCHEMBL17398273 | 0.65 | TSHR (0.47) | TSHRGPR35DAO | |
| SCHEMBL4036013 | 0.65 | TSHR (0.47) | TSHRGPR35DAO | |
| SCHEMBL3495901 | 0.65 | MCL1 (0.49) | HDAC1HDAC8HDAC6 | |
| SCHEMBL23388792 | 0.64 | GPR35 (0.47) | TSHRGPR35DAOHDAC3HDAC4 | |
| SCHEMBL19342527 | 0.64 | GPR35 (0.51) | TSHRGPR35DAOHDAC3HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9701692-B1 | Synthesis of thienothiophenes | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 2017-07-11 | — | — | US | disclosed |