SCHEMBL28811794

SCHEMBL28811794

O=C(O)c1c(Br)sc2c(C(=O)O)c(Br)sc12

nearest known ligand 0.55

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
GPR35 Q9HC97 7/20 0.45
GSK3B P49841 2/20 0.37
DAO P14920 1/20 0.36
TSHR P16473 1/20 0.34
CYP1A2 P05177 1/20 0.32
ALDH1A1 P00352 1/20 0.31
KMT2A Q03164 1/20 0.31
PTPN1 P18031 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1498222 0.82 GSK3B (0.44) GPR35GSK3BDAOTSHRCYP1A2
Hydrochloric Acid SCHEMBL28459433 0.80 GSK3B (0.43) GPR35GSK3BDAOTSHRCYP1A2
SCHEMBL15878019 0.76 GSK3B (0.56) GPR35GSK3BDAOTSHRCYP1A2
SCHEMBL19085034 0.74 TSHR (0.42) GPR35DAOTSHR
SCHEMBL19342527 0.73 GPR35 (0.51) GPR35DAOTSHRALDH1A1KMT2A
SCHEMBL3228565 0.70 POLB (0.47) GPR35DAOALDH1A1KMT2A
SCHEMBL19712733 0.70 GSK3B (0.36) GPR35GSK3BDAOTSHRPTPN1
SCHEMBL19733065 0.67 DAO (0.39) GPR35GSK3BDAOTSHRCYP1A2
SCHEMBL1035933 0.65 CYP1A2 (0.47) GPR35DAOTSHRCYP1A2ALDH1A1
SCHEMBL7529954 0.65 CYP1A2 (0.40) GPR35DAOTSHRCYP1A2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114736232-A Diester-base bithiophene non-condensed ring electron acceptor material, preparation method and application 江西师范大学 2022-07-12 CN claimed
CN-114736232-A Diester-base bithiophene non-condensed ring electron acceptor material, preparation method and application 江西师范大学 2022-07-12 CN disclosed