SCHEMBL5706089

SCHEMBL5706089

CCOc1ccc(C(=O)Oc2ccccc2Cl)cc1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 1/20 0.55
CCNC P24863 2/20 0.53
CDK8 P49336 2/20 0.53
KMT2A Q03164 4/20 0.51
NPC1 O15118 2/20 0.49
RAB9A P51151 1/20 0.49
PARP10 Q53GL7 1/20 0.49
HPGD P15428 3/20 0.48
MEN1 O00255 1/20 0.48
ALDH1A1 P00352 1/20 0.48
NPSR1 Q6W5P4 1/20 0.48
LMNA P02545 1/20 0.48
RXRA P19793 1/20 0.48
RXRB P28702 1/20 0.48
MAOA P21397 1/20 0.47
MAOB P27338 1/20 0.47
MAPT P10636 3/20 0.46
PLK1 P53350 1/20 0.46
PDGFRB P09619 1/20 0.46
PDGFRA P16234 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19281449 0.89 CCNC (0.60) L3MBTL1CCNCCDK8KMT2ANPC1
SCHEMBL5705976 0.89 KMT2A (0.55) L3MBTL1KMT2ANPC1RAB9ALMNA
SCHEMBL5706024 0.85 NPC1 (0.57) L3MBTL1KMT2ANPC1LMNAMAPT
SCHEMBL5706240 0.85 SMN1; SMN2 (0.54) KMT2ANPC1RAB9AHPGDMEN1
SCHEMBL5706248 0.84 HPGD (0.53) KMT2ANPC1RAB9AHPGDMEN1
SCHEMBL17304609 0.84 KMT2A (0.53) CCNCCDK8KMT2ANPC1PARP10
SCHEMBL5705996 0.84 L3MBTL1 (0.56) L3MBTL1KMT2ANPC1RAB9APARP10
SCHEMBL31321713 0.84 HPGD (0.58) L3MBTL1CCNCCDK8KMT2ANPC1
SCHEMBL5706251 0.83 L3MBTL1 (0.58) L3MBTL1KMT2ANPC1RAB9AALDH1A1
SCHEMBL5706123 0.80 TSHR (0.54) L3MBTL1CCNCCDK8KMT2ANPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1304458-C Process for preparing polycarbonate and apparatus for preparing polycarbonate GEN ELECTRIC (US) 2007-03-14 CN disclosed
EP-1412411-B1 PROCESS FOR PREPARING POLYCARBONATE AND APPARATUS FOR PREPARING POLYCARBONATE GEN ELECTRIC (US) 2006-08-09 EP disclosed
CN-1555392-A Method for preparing polycarbonate and apparatus for preparing polycarbonate ͨ�õ�����˾ 2004-12-15 CN disclosed
EP-0976772-B1 PROCESS FOR PRODUCING POLYCARBONATE RESIN TEIJIN LTD (JP) 2004-06-16 EP disclosed
EP-1412411-A2 PROCESS FOR PREPARING POLYCARBONATE AND APPARATUS FOR PREPARING POLYCARBONATE GENERAL ELECTRIC COMPANY (US) 2004-04-28 EP disclosed
CN-1131259-C Method for producing polycarbonate resin TEIJIN LTD (JP) 2003-12-17 CN disclosed
US-6620902-B2 Melting aromatic dihydroxy compound, a carbonic acid diester; mixing with endcapping agent under hermetic sealing GENERAL ELECTRIC COMPANY 2003-09-16 US disclosed
US-20030088051-A1 Process for preparing polycarbonate and apparatus for preparing polycarbonate GENERAL ELECTRIC COMPANY 2003-05-08 US disclosed
WO-2003008481-A2 PROCESS FOR PREPARING POLYCARBONATE AND APPARATUS FOR PREPARING POLYCARBONATE GENERAL ELECTRIC COMPANY (US) 2003-01-30 WO disclosed
US-6303734-B1 HIGH STABILITY TO THE DETERIORATION OF THE COLOR OF CHIPS STORED IN AIR AT ROOM TEMPERATURE BY SUPPRESSING THE RELATIVE INTENSITY OF FLUORESCENT LIGHT TO 4.0 X.10(TO-3) OR BELOW TEIJIN LIMITED (JP) 2001-10-16 US disclosed
CN-1252817-A Process for producing polycarbonate resin TEIJIN LTD (JP) 2000-05-10 CN disclosed
EP-0985696-A1 STABILIZED AROMATIC POLYCARBONATE TEIJIN LIMITED (JP) 2000-03-15 EP disclosed
EP-0976772-A1 PROCESS FOR PRODUCING POLYCARBONATE RESIN TEIJIN LIMITED (JP) 2000-02-02 EP disclosed
EP-0764673-B1 Process for the production of polycarbonate TEIJIN LTD (JP) 1999-11-17 EP disclosed
US-5696222-A MELT POLYCONDENSATION OF AN AROMATIC DIHYDROXY COMPOUND AND DIPHENYLCARBONATE, THEN ADDING A SPECIFIC CARBONATE OR CARBOCYCLIC ESTER TO FORM TERMINAL BLOCKED POLYCARBONATE TEIJIN LIMITED (JP) 1997-12-09 US disclosed
EP-0764673-A2 Process for the production of polycarbonate TEIJIN LIMITED (JP) 1997-03-26 EP disclosed