Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.36 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.34 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19085525 | 0.78 | SLC6A2 (0.40) | SLC6A2SLC6A4CHRM2CHRM4CHRM3 | |
| SCHEMBL2606468 | 0.75 | S1PR3 (0.48) | TSHREPHX1TRPM8KDM4EMEN1 | |
| SCHEMBL4093715 | 0.73 | TAS1R3 (0.35) | SLC6A2SLC6A4CHRM2CHRM4CHRM3 | |
| SCHEMBL28527891 | 0.73 | SLC6A2 (0.50) | SLC6A2SLC6A4CHRM2CHRM4CHRM3 | |
| SCHEMBL19458771 | 0.73 | ALOX5 (0.45) | TSHREPHX1TRPM8KDM4EMEN1 | |
| SCHEMBL2606404 | 0.73 | ALOX5 (0.45) | TSHREPHX1TRPM8KDM4EMEN1 | |
| SCHEMBL11234464 | 0.73 | ALOX5 (0.45) | TSHREPHX1TRPM8KDM4EMEN1 | |
| SCHEMBL2754 | 0.73 | ALOX5 (0.45) | TSHREPHX1TRPM8KDM4EMEN1 | |
| Urea SCHEMBL2807369 | 0.71 | ALOX5 (0.43) | TSHREPHX1TRPM8KDM4EMEN1 | |
| Hydrochloric Acid SCHEMBL13518199 | 0.71 | ALOX5 (0.43) | TSHREPHX1TRPM8KDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2444397-A1 | Heteroaryl-ureas and their use as glucokinase activators | Novo Nordisk A/S (DK) | 2012-04-25 | — | — | EP | disclosed |