SCHEMBL19085969

SCHEMBL19085969

CC(C)S(=O)(=O)c1cccc2c1C=CC(=N)C2=O

nearest known ligand 0.33

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
S100A4 P26447 1/20 0.32
PTPRC P08575 1/20 0.31
ALOX5AP P20292 1/20 0.31
FEN1 P39748 1/20 0.31
ADRA2A P08913 1/20 0.31
ADRA1D P25100 1/20 0.31
ADRA1A P35348 1/20 0.31
ADRA1B P35368 1/20 0.31
SLC2A1 P11166 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14488751 0.82 BAZ2B (0.36) ALDH1A1SMN1; SMN2S100A4PTPRC
SCHEMBL19101741 0.81 PTPRC (0.32) ALDH1A1SMN1; SMN2PTPRC
SCHEMBL18473410 0.79 ALOX15 (0.33) ALDH1A1SMN1; SMN2PTPRC
SCHEMBL22965285 0.79 PSIP1 (0.32) ALDH1A1SMN1; SMN2PTPRCADRA2AADRA1D
SCHEMBL19222627 0.79 S100A4 (0.31) S100A4PTPRC
SCHEMBL19221614 0.79 TTR (0.36) S100A4PTPRC
SCHEMBL19221906 0.79 S100A4 (0.31) S100A4PTPRC
SCHEMBL19368292 0.78 PTPRC (0.37) ALDH1A1SMN1; SMN2PTPRC
SCHEMBL18746467 0.78 CDK5 (0.40) ALDH1A1SMN1; SMN2PTPRCALOX5APFEN1
SCHEMBL24759701 0.76 CA1 (0.38) S100A4PTPRCSLC2A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9932432-B2 Polymers of maleimide and cycloolefinic monomers as permanent dielectric materials PROMERUS, LLC (US) 2018-04-03 US disclosed
WO-2017117483-A1 POLYMERS DERIVED FROM NORBORNADIENE AND MALEIC ANHYDRIDE AND USE THEREOF PROMERUS, LLC (US) 2017-07-06 WO disclosed