Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 4/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.38 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.38 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 5/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | CASP6 | P55212 | 1/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.38 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19086245 | 0.85 | HDAC6 (0.43) | KDM1AALDH1A1L3MBTL1PRMT5WDR77 | |
| SCHEMBL19086213 | 0.85 | KDM1A (0.40) | KDM1AKMT2AALDH1A1LMNAMAPT | |
| SCHEMBL19086202 | 0.84 | KDM1A (0.48) | KDM1AKMT2AALDH1A1LMNAMAPT | |
| SCHEMBL19086204 | 0.84 | ALDH1A1 (0.43) | KDM1AALDH1A1RAB9AL3MBTL1PRMT5 | |
| SCHEMBL19087005 | 0.83 | KDM1A (0.41) | KDM1AALDH1A1L3MBTL1PRMT5WDR77 | |
| SCHEMBL19086203 | 0.81 | PRMT5 (0.40) | KDM1AALDH1A1L3MBTL1PRMT5WDR77 | |
| SCHEMBL19086189 | 0.81 | PRMT5 (0.48) | KDM1AALDH1A1L3MBTL1PRMT5WDR77 | |
| SCHEMBL19086019 | 0.80 | ALDH1A1 (0.41) | KDM1AALDH1A1RAB9AL3MBTL1PRMT5 | |
| SCHEMBL19087010 | 0.80 | KDM1A (0.41) | KDM1AALDH1A1L3MBTL1PRMT5WDR77 | |
| SCHEMBL19086315 | 0.79 | KDM1A (0.47) | KDM1AALDH1A1MAPTNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017114275-A1 | COMPOUND FOR INHIBITING ROCK, PREPARATION METHOD AND USE OF SAME | 成都先导药物开发有限公司 | 2017-07-06 | — | — | WO | disclosed |