Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | KAT2B | Q92831 | 4/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19207549 | 0.79 | KDM4E (0.50) | KDM4EALDH1A1KAT2BHTTPOLB | |
| SCHEMBL31052692 | 0.76 | KDM4E (0.45) | KDM4EALDH1A1HTTPOLBTSHR | |
| SCHEMBL20555773 | 0.76 | CDK9 (0.42) | KDM4EALDH1A1MEN1KMT2AGAA | |
| SCHEMBL8270927 | 0.75 | KDM4E (0.59) | KDM4EALDH1A1HTTPOLBTSHR | |
| SCHEMBL31052600 | 0.74 | KDM4E (0.41) | KDM4EALDH1A1POLBKMT2AGAA | |
| SCHEMBL19207787 | 0.73 | ALDH1A1 (0.42) | ALDH1A1KAT2BTSHRHSD17B10DYRK1A | |
| SCHEMBL22154190 | 0.73 | ALDH1A1 (0.44) | KDM4EALDH1A1KAT2BHTTTSHR | |
| SCHEMBL20555748 | 0.73 | GAA (0.43) | KDM4EALDH1A1TSHRMEN1KMT2A | |
| SCHEMBL2428069 | 0.72 | GLS (0.41) | KDM4EALDH1A1HSD17B10GAAPKM | |
| SCHEMBL31052527 | 0.71 | KDM4E (0.39) | KDM4EALDH1A1POLBKMT2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2999338-B1 | KNOWN AND NOVEL HETEROCYCLIC COMPOUNDS AS PESTICIDES | BAYER CROPSCIENCE AG (DE) | 2017-07-12 | — | — | EP | disclosed |