Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | EGFR | P00533 | 1/20 | 0.40 |
| ▸ | PI4KA | P42356 | 1/20 | 0.40 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.40 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 6/20 | 0.38 |
| ▸ | RAB9A | P51151 | 6/20 | 0.38 |
| ▸ | MAPT | P10636 | 5/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20280414 | 0.74 | ALDH1A1 (0.43) | POLBALDH1A1KDM4EKMT2AMEN1 | |
| SCHEMBL533863 | 0.74 | POLB (0.41) | POLBALDH1A1KDM4EKMT2AMEN1 | |
| SCHEMBL10166462 | 0.74 | MAPK1 (0.41) | POLBALDH1A1KDM4EKMT2AMEN1 | |
| SCHEMBL11316957 | 0.74 | POLB (0.50) | POLBALDH1A1KDM4EKMT2AMEN1 | |
| SCHEMBL7045196 | 0.72 | SMN1; SMN2 (0.43) | POLBALDH1A1KDM4EKMT2AMEN1 | |
| SCHEMBL20033929 | 0.71 | ALDH1A1 (0.45) | POLBALDH1A1KDM4EKMT2AMEN1 | |
| SCHEMBL25778528 | 0.69 | ALDH1A1 (0.47) | POLBALDH1A1KMT2AMEN1CYP1A2 | |
| SCHEMBL21863405 | 0.69 | ALDH1A1 (0.46) | POLBALDH1A1KDM4EKMT2AMEN1 | |
| SCHEMBL6057637 | 0.69 | ALDH1A1 (0.47) | ALDH1A1KDM4EKMT2AMEN1TSHR | |
| SCHEMBL27856470 | 0.69 | POLB (0.41) | POLBALDH1A1KDM4EKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2999338-B1 | KNOWN AND NOVEL HETEROCYCLIC COMPOUNDS AS PESTICIDES | BAYER CROPSCIENCE AG (DE) | 2017-07-12 | — | — | EP | disclosed |