Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 6/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | APAF1 | O14727 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL21847654 | 0.75 | MAPK1 (0.40) | KDM4EPOLBL3MBTL1TAAR1HSD17B10 | |
| SCHEMBL19086926 | 0.73 | KDM4E (0.38) | KDM4EPOLBL3MBTL1HSD17B10MAPT | |
| SCHEMBL30475235 | 0.71 | PIK3CG (0.36) | — | |
| SCHEMBL2817008 | 0.70 | PIK3CG (0.38) | POLBCYP2C19SMN1; SMN2 | |
| SCHEMBL26424364 | 0.69 | PIK3CG (0.37) | — | |
| SCHEMBL11828573 | 0.68 | ALDH1A1 (0.73) | KDM4EPOLBMAPTMEN1CYP2C19 | |
| SCHEMBL7330645 | 0.68 | KDM4E (0.46) | KDM4EPOLBL3MBTL1HSD17B10MAPT | |
| SCHEMBL11620839 | 0.67 | MAPT (0.47) | KDM4EPOLBHSD17B10MAPTTDP1 | |
| SCHEMBL22000962 | 0.67 | PIK3CG (0.36) | — | |
| SCHEMBL173908 | 0.67 | ENPP3 (0.42) | KDM4EPOLBL3MBTL1MAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2999338-B1 | KNOWN AND NOVEL HETEROCYCLIC COMPOUNDS AS PESTICIDES | BAYER CROPSCIENCE AG (DE) | 2017-07-12 | — | — | EP | disclosed |