Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.46 |
| ▸ | MAPT | P10636 | 5/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | GFER | P55789 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL948599 | 0.79 | ALDH1A1 (0.41) | KDM4EMAPTL3MBTL1HSD17B10POLB | |
| SCHEMBL7026979 | 0.75 | KDM4E (0.36) | KDM4EMAPTL3MBTL1HSD17B10POLB | |
| SCHEMBL27357004 | 0.72 | LMNA (0.37) | KDM4EMAPTL3MBTL1HSD17B10POLB | |
| SCHEMBL27654221 | 0.72 | PTGS2 (0.40) | KDM4EMAPTL3MBTL1HSD17B10POLB | |
| SCHEMBL952144 | 0.72 | PTGS2 (0.40) | KDM4EMAPTL3MBTL1HSD17B10POLB | |
| SCHEMBL6525463 | 0.69 | POLB (0.41) | KDM4EMAPTL3MBTL1HSD17B10POLB | |
| SCHEMBL6846384 | 0.69 | ALDH1A1 (0.37) | KDM4EMAPTL3MBTL1RECQLKMT2A | |
| SCHEMBL19086972 | 0.68 | KDM4E (0.40) | KDM4EMAPTL3MBTL1HSD17B10POLB | |
| SCHEMBL4456432 | 0.67 | APEX1 (0.42) | KDM4EMAPTL3MBTL1POLBTDP1 | |
| SCHEMBL3377826 | 0.66 | POLB (0.37) | KDM4EMAPTL3MBTL1HSD17B10POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6342504-B1 | PEPTIDES AS ANTITHROMBINS AND ANTICOAGULANTS | CORVAS INTERNATIONAL, INC. | 2002-01-29 | — | — | US | disclosed |
| US-5656645-A | INHIBITORS OF THROMBIN | CORVAS INTERNATIONAL, INC. (US) | 1997-08-12 | — | — | US | disclosed |
| WO-1996018644-A9 | AROMATIC HETEROCYCLIC DERIVATIVES AS ENZYME INHIBITORS | — | 1996-08-01 | — | — | WO | disclosed |