Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 19/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20059002 | 0.92 | REN (0.42) | REN | |
| SCHEMBL19087210 | 0.90 | REN (0.39) | REN | |
| SCHEMBL17732271 | 0.84 | REN (0.40) | RENALDH1A1SMN1; SMN2 | |
| SCHEMBL17709276 | 0.83 | LMNA (0.37) | RENALDH1A1SMN1; SMN2 | |
| SCHEMBL17721709 | 0.80 | REN (0.37) | RENALDH1A1SMN1; SMN2 | |
| SCHEMBL19087123 | 0.79 | REN (0.47) | REN | |
| SCHEMBL17721710 | 0.78 | PPARA (0.38) | RENALDH1A1SMN1; SMN2 | |
| SCHEMBL29840535 | 0.76 | LMNA (0.38) | REN | |
| SCHEMBL16929845 | 0.76 | LMNA (0.38) | REN | |
| SCHEMBL17261387 | 0.76 | REN (0.48) | REN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017114812-A1 | COMBINATION THERAPY OF AN HBSAG INHIBITOR AND AN INTERFERON | F. HOFFMANN-LA ROCHE AG (CH) | 2017-07-06 | — | — | WO | disclosed |