Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS2 | P35228 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11880935 | 0.85 | — | — | |
| SCHEMBL20204130 | 0.73 | — | — | |
| SCHEMBL10079143 | 0.73 | — | — | |
| SCHEMBL5049512 | 0.72 | SMN1; SMN2 (0.41) | NOS2 | |
| SCHEMBL4636245 | 0.71 | — | — | |
| SCHEMBL20027306 | 0.70 | LMNA (0.50) | NOS2 | |
| SCHEMBL16604395 | 0.69 | LMNA (0.54) | NOS2 | |
| SCHEMBL24983163 | 0.67 | NOS2 (0.31) | NOS2 | |
| SCHEMBL25036850 | 0.67 | ROCK2 (0.35) | NOS2 | |
| SCHEMBL24217467 | 0.67 | LMNA (0.37) | NOS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017117430-A1 | REGULATORS OF THE ENDOPLASMIC RETICULUM PROTEOSTASIS NETWORK | THE SCRIPPS RESEARCH INSTITUTE (US) | 2017-07-06 | — | — | WO | disclosed |