SCHEMBL19087412

SCHEMBL19087412

Cc1cc(C)cc(Nc2c(C)cccc2C)c1

nearest known ligand 0.71

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
RAPGEF4 Q8WZA2 19/20 0.71
ALDH1A1 P00352 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1931619 0.84 NPSR1 (0.63) RAPGEF4ALDH1A1
SCHEMBL14168981 0.81 RAPGEF4 (0.75) RAPGEF4
SCHEMBL3631643 0.81 RAPGEF4 (0.59) RAPGEF4ALDH1A1
SCHEMBL4278475 0.80 ALDH1A1 (0.72) RAPGEF4ALDH1A1
SCHEMBL5134264 0.79 RAPGEF4 (0.68) RAPGEF4ALDH1A1
SCHEMBL18734414 0.78 RAPGEF4 (0.72) RAPGEF4
SCHEMBL2927525 0.77 ALDH1A1 (0.54) RAPGEF4ALDH1A1
SCHEMBL16497558 0.77 RAPGEF4 (0.79) RAPGEF4ALDH1A1
SCHEMBL8014673 0.76 ALDH1A1 (0.61) RAPGEF4ALDH1A1
SCHEMBL10412867 0.76 NPSR1 (0.64) RAPGEF4ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110249030-B Organic electroluminescent device 材料科学有限公司 2023-04-18 CN disclosed
CN-110249030-A Organic electroluminescence device 材料科学有限公司 2019-09-17 CN disclosed
US-20190006592-A1 NOVEL ORGANIC COMPOUND AND ORGANIC ELECTROLUMINESCENT ELEMENT COMPRISING SAME MATERIAL SCIENCE CO., LTD. (KR) 2019-01-03 US disclosed
US-20190006592-A1 NOVEL ORGANIC COMPOUND AND ORGANIC ELECTROLUMINESCENT ELEMENT COMPRISING SAME MATERIAL SCIENCE CO., LTD. (KR) 2019-01-03 US disclosed
WO-2018128470-A1 ORGANIC ELECTROLUMINESCENT ELEMENT 머티어리얼사이언스 주식회사 2018-07-12 WO disclosed
WO-2017116169-A1 NOVEL ORGANIC COMPOUND AND ORGANIC ELECTROLUMINESCENT ELEMENT COMPRISING SAME 머티어리얼사이언스 주식회사 2017-07-06 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190006592-A1 NOVEL ORGANIC COMPOUND AND ORGANIC ELECTROLUMINESCENT ELEMENT COMPRISING SAME OCIAD1, OCIAD2, ORC3 RAPGEF4 2260/4885ALDH1A1 731/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.