Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 16/20 | 0.55 |
| ▸ | CA1 | P00915 | 16/20 | 0.55 |
| ▸ | CA2 | P00918 | 16/20 | 0.55 |
| ▸ | CA9 | Q16790 | 16/20 | 0.55 |
| ▸ | CA4 | P22748 | 15/20 | 0.53 |
| ▸ | CA7 | P43166 | 15/20 | 0.53 |
| ▸ | NAMPT | P43490 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL359836 | 0.93 | CA12 (0.66) | CA12CA1CA2CA9CA4 | |
| SCHEMBL12084865 | 0.93 | CA12 (0.66) | CA12CA1CA2CA9CA4 | |
| SCHEMBL1911231 | 0.83 | EPHX2 (0.62) | MEN1KMT2AGAA | |
| SCHEMBL24381758 | 0.82 | MEN1 (0.67) | MEN1KMT2A | |
| SCHEMBL356730 | 0.81 | CTSL (0.65) | KMT2ASMN1; SMN2 | |
| SCHEMBL358309 | 0.81 | CA12 (0.66) | CA12CA1CA2CA9CA4 | |
| SCHEMBL12084919 | 0.81 | CA12 (0.66) | CA12CA1CA2CA9CA4 | |
| SCHEMBL1911244 | 0.80 | SIGMAR1 (0.61) | MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL359516 | 0.80 | SIGMAR1 (0.61) | MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL1908655 | 0.79 | EPHX1 (0.61) | NAMPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8114877-B2 | Antiinflammatory agnets; chronic obstructive pulmonary diseases | NOVARTIS AG (CH) | 2012-02-14 | — | — | US | disclosed |