Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 5/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.38 |
| ▸ | NAAA | Q02083 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16317495 | 0.93 | SIGMAR1 (0.40) | ALDH1A1SMN1; SMN2MEN1KMT2APOLB | |
| SCHEMBL17532246 | 0.90 | ALDH1A1 (0.47) | ALDH1A1SMN1; SMN2MEN1KMT2APOLB | |
| SCHEMBL16607367 | 0.90 | ALDH1A1 (0.47) | ALDH1A1SMN1; SMN2MEN1KMT2APOLB | |
| SCHEMBL25646717 | 0.86 | SIGMAR1 (0.43) | ALDH1A1SMN1; SMN2MEN1KMT2APOLB | |
| SCHEMBL16749946 | 0.85 | HSD17B10 (0.42) | ALDH1A1SMN1; SMN2MEN1KMT2AS1PR1 | |
| SCHEMBL10063507 | 0.85 | HSD17B10 (0.42) | ALDH1A1SMN1; SMN2MEN1KMT2AS1PR1 | |
| SCHEMBL12004645 | 0.85 | HSD17B10 (0.42) | ALDH1A1SMN1; SMN2MEN1KMT2AS1PR1 | |
| SCHEMBL20260416 | 0.85 | HSD17B10 (0.42) | ALDH1A1SMN1; SMN2MEN1KMT2AS1PR1 | |
| SCHEMBL1041478 | 0.85 | HSD17B10 (0.42) | ALDH1A1SMN1; SMN2MEN1KMT2AS1PR1 | |
| SCHEMBL16317494 | 0.85 | SIGMAR1 (0.44) | ALDH1A1SMN1; SMN2MEN1KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017116994-A1 | UREA-BASED PROSTATE SPECIFIC MEMBRANE ANTIGEN (PSMA) INHIBITORS FOR IMAGING AND THERAPY | FIVE ELEVEN PHARMA INC. (US) | 2017-07-06 | — | — | WO | disclosed |
| US-20170189568-A1 | UREA-BASED PROSTATE SPECIFIC MEMBRANE ANTIGEN (PSMA) INHIBITORS FOR IMAGING AND THERAPY | FIVE ELEVEN PHARMA INC. | 2017-07-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170189568-A1 | UREA-BASED PROSTATE SPECIFIC MEMBRANE ANTIGEN (PSMA) INHIBITORS FOR IMAGING AND THERAPY | KLK3, FOLH1, UTS2R | ALDH1A1 1860/4885SMN1; SMN2 4514/4885MEN1 411/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.