Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.43 |
| ▸ | NAAA | Q02083 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17532246 | 1.00 | ALDH1A1 (0.47) | ALDH1A1SMN1; SMN2MEN1KMT2APOLB | |
| SCHEMBL16607366 | 0.93 | MEN1 (0.49) | ALDH1A1SMN1; SMN2MEN1KMT2APOLB | |
| SCHEMBL30839344 | 0.93 | MEN1 (0.49) | ALDH1A1SMN1; SMN2MEN1KMT2APOLB | |
| SCHEMBL15775872 | 0.91 | SIGMAR1 (0.46) | ALDH1A1SMN1; SMN2MEN1KMT2APOLB | |
| SCHEMBL25260908 | 0.91 | SIGMAR1 (0.46) | ALDH1A1SMN1; SMN2MEN1KMT2APOLB | |
| SCHEMBL21257065 | 0.90 | PAM (0.49) | ALDH1A1SMN1; SMN2MEN1KMT2APOLB | |
| SCHEMBL19088250 | 0.90 | ALDH1A1 (0.40) | ALDH1A1SMN1; SMN2MEN1KMT2APOLB | |
| SCHEMBL24322437 | 0.89 | ALDH1A1 (0.47) | ALDH1A1SMN1; SMN2MEN1KMT2APOLB | |
| SCHEMBL10852328 | 0.86 | THRA (0.47) | ALDH1A1SMN1; SMN2MEN1KMT2APOLB | |
| SCHEMBL11855822 | 0.86 | NAAA (0.60) | ALDH1A1SMN1; SMN2MEN1KMT2ANAAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170128572-A1 | LONG-LIVED GADOLINIUM BASED TUMOR TARGETED IMAGING AND THERAPY AGENTS | WISCONSIN ALUMNI RESEARCH FOUNDATION | 2017-05-11 | — | — | US | disclosed |
| US-20160199520-A1 | NOVEL NITROGEN-CONTAINING COMPOUND OR SALT THEREOF, OR METAL COMPLEX THEREOF | FUJIFILM CORPORATION (JP) | 2016-07-14 | — | — | US | disclosed |
| WO-2015046278-A1 | NOVEL NITROGEN-CONTAINING COMPOUND OR SALT THEREOF, OR METAL COMPLEX THEREOF | 富士フイルム株式会社 | 2015-04-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170128572-A1 | LONG-LIVED GADOLINIUM BASED TUMOR TARGETED IMAGING AND THERAPY AGENTS | H1-3, H1-2, H1-4 | ALDH1A1 3398/4885SMN1; SMN2 2638/4885MEN1 529/4885 |
| US-20160199520-A1 | NOVEL NITROGEN-CONTAINING COMPOUND OR SALT THEREOF, OR METAL COMPLEX THEREOF | SLC39A3, SLC39A14, SLC39A11 | ALDH1A1 3116/4885SMN1; SMN2 2615/4885MEN1 45/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.