Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AAK1 | Q2M2I8 | 3/20 | 0.34 |
| ▸ | MMP13 | P45452 | 1/20 | 0.34 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.31 |
| ▸ | CTSK | P43235 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18248055 | 0.87 | MMP13 (0.37) | AAK1MMP13CA14HDAC1HDAC2 | |
| SCHEMBL18248003 | 0.87 | MMP13 (0.37) | AAK1MMP13CA14HDAC1HDAC2 | |
| SCHEMBL18248194 | 0.84 | AAK1 (0.36) | AAK1MMP13CA14CTSK | |
| SCHEMBL18248195 | 0.84 | AAK1 (0.36) | AAK1MMP13CA14CTSK | |
| SCHEMBL20166246 | 0.83 | NFKB1 (0.35) | AAK1MMP13CA14HDAC1HDAC2 | |
| SCHEMBL19088621 | 0.81 | AAK1 (0.34) | AAK1MMP13CA14 | |
| SCHEMBL13335431 | 0.81 | AAK1 (0.36) | AAK1MMP13CA14HDAC1HDAC2 | |
| SCHEMBL14831511 | 0.81 | AAK1 (0.36) | AAK1MMP13CA14HDAC1HDAC2 | |
| SCHEMBL19088592 | 0.79 | CA14 (0.39) | AAK1MMP13CA14HDAC1HDAC2 | |
| SCHEMBL26034208 | 0.79 | AAK1 (0.33) | AAK1MMP13CA14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017116702-A1 | ANTHELMINTIC DEPSIPEPTIDE COMPOUNDS | MERIAL, INC. (US) | 2017-07-06 | — | — | WO | disclosed |