SCHEMBL19088593

SCHEMBL19088593

CCC(C)(C)OC(=O)N1CCOC1(C)C

nearest known ligand 0.34

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
USP2 O75604 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
SPHK1 Q9NYA1 1/20 0.31
TSHR P16473 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2224518 0.85 USP2 (0.47) USP2SMN1; SMN2SPHK1
SCHEMBL25793602 0.72 USP2 (0.41) USP2SMN1; SMN2TSHR
SCHEMBL3042385 0.71 TSHR (0.30) TSHR
SCHEMBL14802585 0.71 SMN1; SMN2 (0.66) USP2SMN1; SMN2TSHR
SCHEMBL1855329 0.71 SMN1; SMN2 (0.46) USP2SMN1; SMN2TSHR
SCHEMBL11310663 0.71
SCHEMBL9852425 0.70 SMN1; SMN2 (0.38) SMN1; SMN2
SCHEMBL2634417 0.69 SMN1; SMN2 (0.32) SMN1; SMN2
SCHEMBL1848025 0.68 HPGD (0.47) USP2SMN1; SMN2TSHR
SCHEMBL879545 0.67 HPGD (0.50) USP2SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3397638-B1 ANTHELMINTIC DEPSIPEPTIDE COMPOUNDS BOEHRINGER INGELHEIM ANIMAL HEALTH USA INC (US) 2023-08-23 EP disclosed
WO-2017116702-A1 ANTHELMINTIC DEPSIPEPTIDE COMPOUNDS MERIAL, INC. (US) 2017-07-06 WO disclosed