Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR2 | P21802 | 1/20 | 0.44 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.44 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.44 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | SYK | P43405 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | TYR | P14679 | 1/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.39 |
| ▸ | WDR5 | P61964 | 8/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3784306 | 0.84 | ALDH1A1 (0.49) | KDM4ESMN1; SMN2KMT2ACA12CA1 | |
| SCHEMBL3784304 | 0.84 | ALDH1A1 (0.49) | KDM4ESMN1; SMN2KMT2ACA12CA1 | |
| SCHEMBL23279523 | 0.83 | NR3C2 (0.40) | FGFR2FGFR3ACVR1NR3C2SYK | |
| SCHEMBL16067901 | 0.80 | NR3C2 (0.46) | FGFR2FGFR3ACVR1NR3C2SMN1; SMN2 | |
| SCHEMBL4622159 | 0.79 | CA12 (0.47) | KDM4ESMN1; SMN2KMT2ACA12CA1 | |
| SCHEMBL29547544 | 0.76 | NPSR1 (0.46) | KDM4ESMN1; SMN2KMT2ACA12CA1 | |
| SCHEMBL27739984 | 0.73 | ALDH1A1 (0.50) | FGFR2FGFR3ACVR1NR3C2KDM4E | |
| SCHEMBL14376036 | 0.73 | NR3C2 (0.47) | FGFR2FGFR3ACVR1NR3C2KDM4E | |
| SCHEMBL20120950 | 0.73 | HDAC1 (0.45) | KDM4ESMN1; SMN2KMT2ACA12CA1 | |
| SCHEMBL20128887 | 0.72 | GPR119 (0.52) | SMN1; SMN2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3397638-B1 | ANTHELMINTIC DEPSIPEPTIDE COMPOUNDS | BOEHRINGER INGELHEIM ANIMAL HEALTH USA INC (US) | 2023-08-23 | — | — | EP | disclosed |
| WO-2017116702-A1 | ANTHELMINTIC DEPSIPEPTIDE COMPOUNDS | MERIAL, INC. (US) | 2017-07-06 | — | — | WO | disclosed |