Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APEX1 | P27695 | 2/20 | 0.42 |
| ▸ | CHKA | P35790 | 3/20 | 0.42 |
| ▸ | TERT | O14746 | 2/20 | 0.37 |
| ▸ | KCNN3 | Q9UGI6 | 1/20 | 0.33 |
| ▸ | IKBKB | O14920 | 2/20 | 0.32 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.32 |
| ▸ | KCNN1 | Q92952 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21955684 | 1.00 | APEX1 (0.42) | APEX1CHKATERTKCNN3IKBKB | |
| SCHEMBL4359812 | 1.00 | — | — | |
| SCHEMBL4946987 | 0.92 | CHKA (0.38) | APEX1CHKATERTKCNN3 | |
| SCHEMBL18128899 | 0.86 | APEX1 (0.60) | APEX1CHKATERT | |
| SCHEMBL29386754 | 0.86 | APEX1 (0.60) | APEX1CHKATERT | |
| SCHEMBL30050918 | 0.86 | APEX1 (0.60) | APEX1CHKATERT | |
| SCHEMBL16259451 | 0.77 | APEX1 (0.44) | APEX1CHKATERT | |
| SCHEMBL9566479 | 0.75 | ACHE (0.43) | APEX1TERTKCNN3 | |
| SCHEMBL3113400 | 0.72 | ACHE (0.39) | APEX1TERT | |
| SCHEMBL6515380 | 0.71 | APEX1 (0.45) | APEX1CHKATERT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017116272-A1 | METHOD FOR PREPARING TERTIARY AMINES COMPRISING ETHYNYLBENZYL SUBSTITUENTS | PUBLIC JOINT STOCK COMPANY "SIBUR HOLDING" (RU) | 2017-07-06 | — | — | WO | disclosed |