Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APEX1 | P27695 | 2/20 | 0.45 |
| ▸ | TERT | O14746 | 2/20 | 0.40 |
| ▸ | CHKA | P35790 | 3/20 | 0.37 |
| ▸ | PNMT | P11086 | 2/20 | 0.34 |
| ▸ | CD44 | P16070 | 2/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | JAK2 | O60674 | 3/20 | 0.31 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.31 |
| ▸ | CDK2 | P24941 | 1/20 | 0.31 |
| ▸ | FLT3 | P36888 | 1/20 | 0.31 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.31 |
| ▸ | PKN2 | Q16513 | 1/20 | 0.31 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.31 |
| ▸ | JAK1 | P23458 | 2/20 | 0.31 |
| ▸ | JAK3 | P52333 | 2/20 | 0.31 |
| ▸ | TYK2 | P29597 | 1/20 | 0.31 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.31 |
| ▸ | HTR2C | P28335 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29386754 | 0.80 | APEX1 (0.60) | APEX1TERTCHKAPNMTCD44 | |
| SCHEMBL18128899 | 0.80 | APEX1 (0.60) | APEX1TERTCHKAPNMTCD44 | |
| SCHEMBL30050918 | 0.80 | APEX1 (0.60) | APEX1TERTCHKAPNMTCD44 | |
| Hydrogen Sulfide SCHEMBL28492811 | 0.78 | — | — | |
| Naphthalene SCHEMBL11585432 | 0.72 | CHKA (0.46) | APEX1CHKAJAK2NISCHJAK1 | |
| SCHEMBL21955684 | 0.71 | APEX1 (0.42) | APEX1TERTCHKA | |
| SCHEMBL19089065 | 0.71 | APEX1 (0.42) | APEX1TERTCHKA | |
| SCHEMBL4359812 | 0.71 | — | — | |
| SCHEMBL9566479 | 0.69 | ACHE (0.43) | APEX1TERTPNMTCD44MAOB | |
| Ethylamine SCHEMBL17061531 | 0.69 | CHKA (0.43) | CHKAJAK2JAK1JAK3TYK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050171094-A1 | Pyrrolopyrimidine derivatives | TEIJIN, LIMITED (JP) | 2005-08-04 | — | — | US | disclosed |
| EP-1477490-A1 | PYRROLOPYRIMIDINE DERIVATIVE | TEIJIN LIMITED (JP) | 2004-11-17 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050171094-A1 | Pyrrolopyrimidine derivatives | GSK3B, GSK3A, GSKIP | APEX1 4225/4885TERT 3035/4885CHKA 918/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.