Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | KDM1A | O60341 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | CTSD | P07339 | 1/20 | 0.34 |
| ▸ | BCHE | P06276 | 2/20 | 0.33 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.33 |
| ▸ | CKS1B | P61024 | 1/20 | 0.33 |
| ▸ | SKP1 | P63208 | 1/20 | 0.33 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17898811 | 0.88 | GAA (0.38) | GAAKMT2AL3MBTL1KDM1AMAOB | |
| SCHEMBL15373333 | 0.86 | KMT2A (0.38) | GAAKMT2AL3MBTL1BCHE | |
| SCHEMBL17898648 | 0.85 | BCHE (0.37) | GAAKMT2AL3MBTL1KDM1AMAOB | |
| SCHEMBL17899063 | 0.85 | GAA (0.39) | GAACTSD | |
| SCHEMBL19089218 | 0.83 | GAA (0.46) | GAAKMT2AL3MBTL1CTSD | |
| SCHEMBL15373856 | 0.81 | BCHE (0.39) | GAACTSDBCHE | |
| SCHEMBL17898835 | 0.81 | OPRK1 (0.34) | KMT2ABCHE | |
| SCHEMBL17898809 | 0.80 | GAA (0.39) | GAACTSD | |
| SCHEMBL17899036 | 0.78 | ROCK1 (0.31) | — | |
| SCHEMBL17903383 | 0.77 | KMT2A (0.37) | GAAKMT2AL3MBTL1KDM1AMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016109291-A1 | USE OF MACROCYCLIC PICOLINAMIDES AS FUNGICIDES | DOW AGROSCIENCES LLC (US) | 2016-07-07 | — | — | WO | disclosed |
| WO-2016109290-A1 | MACROCYCLIC PICOLINAMIDE COMPOUNDS WITH FUNGICIDAL ACTIVITY | DOW AGROSCIENCES LLC (US) | 2016-07-07 | — | — | WO | disclosed |