Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 16/20 | 0.59 |
| ▸ | KDR | P35968 | 5/20 | 0.59 |
| ▸ | ABL1 | P00519 | 1/20 | 0.45 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.45 |
| ▸ | KIT | P10721 | 1/20 | 0.45 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.45 |
| ▸ | SRC | P12931 | 1/20 | 0.45 |
| ▸ | BRAF | P15056 | 1/20 | 0.45 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.45 |
| ▸ | TEK | Q02763 | 1/20 | 0.45 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.43 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.43 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19089509 | 0.82 | EGFR (0.61) | EGFRKDRABL1KITFGFR1 | |
| SCHEMBL19089675 | 0.79 | EGFR (0.49) | EGFRKDRABL1PDGFRBSRC | |
| SCHEMBL28056977 | 0.77 | EGFR (0.55) | EGFRKDRPDGFRBBRAFEPHB4 | |
| SCHEMBL2203223 | 0.77 | EGFR (0.55) | EGFRKDRPDGFRBBRAFEPHB4 | |
| SCHEMBL19089668 | 0.77 | EGFR (0.54) | EGFRKDR | |
| SCHEMBL11727 | 0.75 | EGFR (1.00) | EGFRKDRPDGFRBEPHB4TEK | |
| SCHEMBL19089515 | 0.75 | GALR2 (0.49) | EGFRKDRPDGFRBSRCEPHB4 | |
| SCHEMBL19089517 | 0.74 | EGFR (0.59) | EGFRKDRFGFR1ERBB2 | |
| SCHEMBL35210320 | 0.74 | EGFR (0.59) | EGFRKDRFGFR1ERBB2 | |
| SCHEMBL7777464 | 0.74 | EGFR (0.61) | EGFRKDRPDGFRBBRAFEPHB4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017114500-A1 | ACRYLANILIDE DERIVATIVE, PREPARATION METHOD THEREFOR, AND APPLICATIONS THEREOF IN PHARMACY | 恩瑞生物医药科技（上海）有限公司 | 2017-07-06 | — | — | WO | disclosed |