Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.68 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 4/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20655720 | 0.84 | L3MBTL1 (0.60) | L3MBTL1SMN1; SMN2MEN1KMT2ALMNA | |
| SCHEMBL13899145 | 0.83 | CASR (0.52) | L3MBTL1SMN1; SMN2MEN1KMT2ALMNA | |
| SCHEMBL2371573 | 0.81 | L3MBTL1 (1.00) | L3MBTL1SMN1; SMN2MEN1KMT2ALMNA | |
| SCHEMBL12179265 | 0.81 | L3MBTL1 (0.70) | L3MBTL1SMN1; SMN2MEN1KMT2ALMNA | |
| SCHEMBL10641260 | 0.79 | L3MBTL1 (0.68) | L3MBTL1SMN1; SMN2MEN1KMT2AHTT | |
| SCHEMBL25976983 | 0.79 | L3MBTL1 (0.68) | L3MBTL1SMN1; SMN2MEN1KMT2ALMNA | |
| SCHEMBL6832226 | 0.79 | L3MBTL1 (0.68) | L3MBTL1SMN1; SMN2MEN1KMT2ALMNA | |
| SCHEMBL15546364 | 0.79 | SMN1; SMN2 (0.69) | L3MBTL1SMN1; SMN2KMT2AGAAGLA | |
| SCHEMBL5711921 | 0.79 | L3MBTL1 (0.43) | L3MBTL1SMN1; SMN2MEN1KMT2ALMNA | |
| SCHEMBL13167572 | 0.78 | L3MBTL1 (0.66) | L3MBTL1SMN1; SMN2MEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017114500-A1 | ACRYLANILIDE DERIVATIVE, PREPARATION METHOD THEREFOR, AND APPLICATIONS THEREOF IN PHARMACY | 恩瑞生物医药科技（上海）有限公司 | 2017-07-06 | — | — | WO | disclosed |