Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.68 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12179265 | 0.81 | L3MBTL1 (0.70) | L3MBTL1SMN1; SMN2KMT2AMEN1NPSR1 | |
| SCHEMBL2371573 | 0.81 | L3MBTL1 (1.00) | L3MBTL1SMN1; SMN2KMT2AMEN1NPSR1 | |
| SCHEMBL14411400 | 0.80 | SMN1; SMN2 (0.65) | L3MBTL1SMN1; SMN2GLAKMT2AMEN1 | |
| SCHEMBL6832226 | 0.79 | L3MBTL1 (0.68) | L3MBTL1SMN1; SMN2KMT2AMEN1NPSR1 | |
| SCHEMBL19089644 | 0.79 | L3MBTL1 (0.68) | L3MBTL1SMN1; SMN2GLAKMT2AMEN1 | |
| SCHEMBL15546364 | 0.79 | SMN1; SMN2 (0.69) | L3MBTL1SMN1; SMN2GLAKMT2AGAA | |
| SCHEMBL10641260 | 0.79 | L3MBTL1 (0.68) | L3MBTL1SMN1; SMN2GLAKMT2AMEN1 | |
| SCHEMBL14047981 | 0.79 | TRPV4 (0.51) | L3MBTL1SMN1; SMN2GLAKMT2ANPSR1 | |
| SCHEMBL13167572 | 0.78 | L3MBTL1 (0.66) | L3MBTL1SMN1; SMN2GLAKMT2AMEN1 | |
| SCHEMBL11514317 | 0.78 | L3MBTL1 (0.66) | L3MBTL1SMN1; SMN2KMT2AMEN1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023146513-A1 | COMPOUNDS AND METHODS OF USE THEREOF | VIVACE THERAPEUTICS, INC. (US) | 2023-08-03 | — | — | WO | disclosed |