SCHEMBL2371573

SCHEMBL2371573

CNS(=O)(=O)c1cc(OC)ccc1OC

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 1/20 1.00
SMN1; SMN2 Q16637 5/20 0.61
MAPT P10636 2/20 0.61
KMT2A Q03164 2/20 0.61
GAA P10253 1/20 0.61
MAPK1 P28482 1/20 0.61
TP53 P04637 1/20 0.61
ALDH1A1 P00352 6/20 0.60
NPSR1 Q6W5P4 2/20 0.60
MEN1 O00255 1/20 0.58
LMNA P02545 1/20 0.58
ALOX12 P18054 1/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL417679 0.84 L3MBTL1 (0.73) L3MBTL1SMN1; SMN2MAPTKMT2AGAA
SCHEMBL2371570 0.84 L3MBTL1 (0.73) L3MBTL1SMN1; SMN2MAPTKMT2AGAA
SCHEMBL31213824 0.82 L3MBTL1 (0.70) L3MBTL1SMN1; SMN2GAAALDH1A1NPSR1
SCHEMBL12179265 0.82 L3MBTL1 (0.70) L3MBTL1SMN1; SMN2KMT2AGAAMAPK1
SCHEMBL5962567 0.81 ALDH1A1 (0.74) L3MBTL1SMN1; SMN2MAPTKMT2AGAA
SCHEMBL13079743 0.81 SMN1; SMN2 (0.70) L3MBTL1SMN1; SMN2MAPTGAAALDH1A1
SCHEMBL13049842 0.81 L3MBTL1 (0.69) L3MBTL1SMN1; SMN2MAPTKMT2AGAA
SCHEMBL18530465 0.81 SMN1; SMN2 (0.79) L3MBTL1SMN1; SMN2KMT2AGAAMAPK1
SCHEMBL7893544 0.81 L3MBTL1 (0.67) L3MBTL1SMN1; SMN2MAPTKMT2AGAA
SCHEMBL15546364 0.81 SMN1; SMN2 (0.69) L3MBTL1SMN1; SMN2KMT2AGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2547204-A2 ARYL AND HETARYL SULFONAMIDES AS ACTIVE AGENTS AGAINST ABIOTIC PLANT STRESS Bayer Intellectual Property GmbH (DE) 2013-01-23 EP claimed
US-20110230350-A1 ARYL-AND HETARYLSULFONAMIDES AS ACTIVE INGREDIENTS AGAINST ABIOTIC PLANT STRESS BAYER CROPSCIENCE AG (DE) 2011-09-22 US claimed
WO-2011113861-A2 ARYL AND HETARYL SULFONAMIDES AS ACTIVE AGENTS AGAINST ABIOTIC PLANT STRESS BAYER CROPSCIENCE AG (DE) 2011-09-22 WO claimed
EP-4692249-A1 COLORING AGENT, COLORING COMPOSITION, AND METHOD FOR PRODUCING COLORING AGENT Artience Co., Ltd. (JP) 2026-02-11 EP disclosed
WO-2024204597-A1 COLORING AGENT, COLORING COMPOSITION, AND METHOD FOR PRODUCING COLORING AGENT artience株式会社 2024-10-03 WO disclosed
US-9095590-B2 Anti-infective agents and uses thereof ABBVIE INC. (US) 2015-08-04 US disclosed
US-20140235638-A1 Anti-Infective Agents and Uses Thereof ABBVIE INC. (US) 2014-08-21 US disclosed
US-8415351-B2 Anti-infective agents and uses thereof ABBOTT LABORATORIES (US) 2013-04-09 US disclosed
EP-2547204-A2 ARYL AND HETARYL SULFONAMIDES AS ACTIVE AGENTS AGAINST ABIOTIC PLANT STRESS Bayer Intellectual Property GmbH (DE) 2013-01-23 EP disclosed
US-20120213733-A1 ANTI-INFECTIVE AGENTS AND USES THEREOF ABBOTT LABORATORIES (US) 2012-08-23 US disclosed
US-20110230350-A1 ARYL-AND HETARYLSULFONAMIDES AS ACTIVE INGREDIENTS AGAINST ABIOTIC PLANT STRESS BAYER CROPSCIENCE AG (DE) 2011-09-22 US disclosed
WO-2011113861-A2 ARYL AND HETARYL SULFONAMIDES AS ACTIVE AGENTS AGAINST ABIOTIC PLANT STRESS BAYER CROPSCIENCE AG (DE) 2011-09-22 WO disclosed
US-20110070193-A1 Anti-Infective Agents and Uses Thereof ABBOTT LABORATORIES (US) 2011-03-24 US disclosed
WO-2009039127-A1 URACIL OR THYMINE DERIVATIVE FOR TREATING HEPATITIS C ABBOTT LABORATORIES (US) 2009-03-26 WO disclosed
EP-1587585-B1 ACYLSULFONAMIDE COMPOUNDS AS INHIBITORS OF RNA-DEPENDENT RNA (VIRAL) POLYMERASES BOEHRINGER INGELHEIM INT (DE) 2008-10-15 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110070193-A1 Anti-Infective Agents and Uses Thereof MPO, SERPINB1, ELANE L3MBTL1 2449/4885SMN1; SMN2 4700/4885MAPT 4320/4885
US-20120213733-A1 ANTI-INFECTIVE AGENTS AND USES THEREOF MPO, SERPINB1, ELANE L3MBTL1 2449/4885SMN1; SMN2 4700/4885MAPT 4320/4885
US-20110230350-A1 ARYL-AND HETARYLSULFONAMIDES AS ACTIVE INGREDIENTS AGAINST ABIOTIC PLANT STRESS STS, ARSA, TST L3MBTL1 3916/4885SMN1; SMN2 4603/4885MAPT 4663/4885
US-20140235638-A1 Anti-Infective Agents and Uses Thereof MPO, ELANE, LPO L3MBTL1 2587/4885SMN1; SMN2 4666/4885MAPT 4075/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.