Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19090235 | 0.78 | KMT2A (0.44) | — | |
| SCHEMBL21389505 | 0.71 | BRD4 (0.46) | — | |
| SCHEMBL19090462 | 0.65 | P2RX3 (0.35) | LMNA | |
| SCHEMBL19090395 | 0.65 | ADAMTS5 (0.35) | LMNA | |
| SCHEMBL19090465 | 0.65 | MEN1 (0.39) | LMNA | |
| SCHEMBL19090394 | 0.64 | P2RX3 (0.34) | — | |
| SCHEMBL19090459 | 0.64 | MEN1 (0.49) | — | |
| SCHEMBL19090407 | 0.62 | P2RX3 (0.36) | — | |
| SCHEMBL19090597 | 0.62 | ALDH1A1 (0.45) | — | |
| SCHEMBL19090326 | 0.61 | NPSR1 (0.47) | LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017114843-A1 | XANTHINE DERIVATIVE INHIBITORS OF BET PROTEINS | INSERM (Institut National de la Santé et de la Recherche Médicale) (FR) | 2017-07-06 | — | — | WO | disclosed |