Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX3 | P56373 | 8/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.30 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.30 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.30 |
| ▸ | ACP1 | P24666 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19090394 | 0.82 | P2RX3 (0.34) | P2RX3MEN1POLBKMT2ASMN1; SMN2 | |
| SCHEMBL19090407 | 0.74 | P2RX3 (0.36) | P2RX3MEN1POLBKMT2APTPN2 | |
| SCHEMBL19090465 | 0.73 | MEN1 (0.39) | P2RX3MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL19090462 | 0.72 | P2RX3 (0.35) | P2RX3MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL19090597 | 0.69 | ALDH1A1 (0.45) | P2RX3MEN1KMT2A | |
| SCHEMBL19090399 | 0.68 | MEN1 (0.42) | MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL19090464 | 0.67 | P2RX3 (0.36) | P2RX3MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL19090596 | 0.67 | KMT2A (0.34) | P2RX3MEN1KMT2ASMN1; SMN2PTPN1 | |
| SCHEMBL19090593 | 0.67 | BRD4 (0.34) | — | |
| SCHEMBL19090459 | 0.67 | MEN1 (0.49) | MEN1POLBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017114843-A1 | XANTHINE DERIVATIVE INHIBITORS OF BET PROTEINS | INSERM (Institut National de la Santé et de la Recherche Médicale) (FR) | 2017-07-06 | — | — | WO | disclosed |