Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.38 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.37 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.37 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | PLD3 | Q8IV08 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | P2RX3 | P56373 | 2/20 | 0.34 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.34 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.34 |
| ▸ | APEX1 | P27695 | 1/20 | 0.34 |
| ▸ | PRNP | P04156 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19090457 | 0.76 | MAPT (0.37) | KDM4EMAPTLMNAGAAAPEX1 | |
| SCHEMBL19090547 | 0.69 | SMN1; SMN2 (0.38) | KDM4EMAPTLMNAGAATSHR | |
| SCHEMBL19090553 | 0.63 | SMN1; SMN2 (0.37) | KDM4EMAPTLMNAGAAHTT | |
| SCHEMBL19090465 | 0.63 | MEN1 (0.39) | KDM4EMAPTL3MBTL1LMNAGAA | |
| SCHEMBL19090464 | 0.62 | P2RX3 (0.36) | MAPK1KDM4EMAPTLMNAGAA | |
| SCHEMBL8290551 | 0.62 | TSHR (0.78) | MAPK1LMNATSHR | |
| SCHEMBL19090462 | 0.62 | P2RX3 (0.35) | KDM4EMAPTLMNAGAAHTT | |
| SCHEMBL15575018 | 0.61 | GPR84 (0.61) | GPR84MAPTL3MBTL1LMNAGAA | |
| SCHEMBL13516893 | 0.60 | KDM4E (0.72) | MAPK1KDM4EMAPTL3MBTL1LMNA | |
| SCHEMBL909499 | 0.59 | HPGD (0.60) | KDM4EMAPTL3MBTL1LMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017114843-A1 | XANTHINE DERIVATIVE INHIBITORS OF BET PROTEINS | INSERM (Institut National de la Santé et de la Recherche Médicale) (FR) | 2017-07-06 | — | — | WO | disclosed |