Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 16/20 | 0.51 |
| ▸ | PPARA | Q07869 | 16/20 | 0.51 |
| ▸ | PPARG | P37231 | 12/20 | 0.49 |
| ▸ | SCD | O00767 | 3/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | PKLR | P30613 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1909733 | 0.87 | SCD (0.52) | PPARDPPARAPPARGSCDPKM | |
| SCHEMBL1909734 | 0.84 | ROCK2 (0.45) | PPARDPPARAPPARGSCDPKM | |
| SCHEMBL1909737 | 0.82 | PPARA (0.47) | PPARDPPARAPPARGSCDPKM | |
| SCHEMBL242950 | 0.78 | PPARD (0.55) | PPARDPPARAPPARGSCD | |
| SCHEMBL27837939 | 0.75 | SCD (0.61) | PPARDPPARAPPARGSCD | |
| SCHEMBL245289 | 0.74 | PPARD (0.51) | PPARDPPARAPPARGSCD | |
| SCHEMBL5906346 | 0.73 | PPARD (0.64) | PPARDPPARAPPARG | |
| SCHEMBL1909735 | 0.71 | DRD2 (0.31) | SCD | |
| SCHEMBL245267 | 0.71 | SCD (0.68) | PPARDPPARAPPARGSCD | |
| SCHEMBL7944039 | 0.70 | PPARD (0.55) | PPARDPPARAPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8293768-B2 | Organic compounds | NOVARTIS AG (CH) | 2012-10-23 | — | — | US | disclosed |
| US-20120004164-A1 | ORGANIC COMPOUNDS | XENON PHARMACEUTICALS INC. (CA) | 2012-01-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120004164-A1 | ORGANIC COMPOUNDS | SCD, SCD5, FADS2 | PPARD 33/4885PPARA 51/4885PPARG 28/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.