Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GNAI3 | P08754 | 1/20 | 0.50 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.50 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.50 |
| ▸ | SLC6A1 | P30531 | 2/20 | 0.46 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.46 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.46 |
| ▸ | SLC6A12 | P48065 | 2/20 | 0.46 |
| ▸ | SLC6A11 | P48066 | 2/20 | 0.46 |
| ▸ | SLC6A13 | Q9NSD5 | 2/20 | 0.46 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.46 |
| ▸ | GABRR1 | P24046 | 1/20 | 0.46 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.46 |
| ▸ | SAT1 | P21673 | 1/20 | 0.37 |
| ▸ | KDM1A | O60341 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.34 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.34 |
| ▸ | ANPEP | P15144 | 1/20 | 0.33 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.33 |
| ▸ | SMYD3 | Q9H7B4 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9687891 | 0.88 | SLC6A1 (0.48) | GNAI3GNAO1GNAI1SLC6A1GABRA5 | |
| SCHEMBL8135765 | 0.81 | GNAO1 (0.75) | GNAI3GNAO1GNAI1SLC6A1GABRA5 | |
| SCHEMBL15700835 | 0.81 | GNAI3 (0.69) | GNAI3GNAO1GNAI1SLC6A1GABRA5 | |
| SCHEMBL10688701 | 0.78 | SLC6A1 (0.47) | GNAI3GNAO1GNAI1SLC6A1GABRA5 | |
| SCHEMBL6968840 | 0.78 | GNAI3 (0.56) | GNAI3GNAO1GNAI1SLC6A1GABRA5 | |
| SCHEMBL25582070 | 0.78 | GNAI3 (0.56) | GNAI3GNAO1GNAI1SLC6A1GABRA5 | |
| SCHEMBL5963013 | 0.77 | GNAI3 (0.75) | GNAI3GNAO1GNAI1SLC6A1GABRA5 | |
| SCHEMBL3427404 | 0.77 | — | — | |
| SCHEMBL1431005 | 0.75 | — | — | |
| SCHEMBL669897 | 0.75 | GNAI3 (0.56) | GNAI3GNAO1GNAI1SLC6A1GABRA5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3400228-A1 | FUSED QUADRACYCLIC COMPOUNDS, COMPOSITIONS AND USES THEREOF | Tabomedex Biosciences, LLC (US) | 2018-11-14 | — | — | EP | disclosed |
| WO-2017120164-A1 | FUSED QUADRACYCLIC COMPOUNDS, COMPOSITIONS AND USES THEREOF | Tabomedex Biosciences, LLC (US) | 2017-07-13 | — | — | WO | disclosed |