Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.43 |
| ▸ | IKBKB | O14920 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | CASP3 | P42574 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19064181 | 0.82 | KDR (0.44) | KDM4EALDH1A1HSD17B10GAAALOX15 | |
| SCHEMBL20141700 | 0.71 | KDM4E (0.36) | KDM4EALDH1A1HSD17B10GAAMAPT | |
| SCHEMBL12582220 | 0.71 | NR4A2 (0.46) | KDM4EALDH1A1GAAMAPTRAB9A | |
| SCHEMBL19063822 | 0.70 | LDHA (0.42) | KDM4EALDH1A1HSD17B10ALOX15MAPT | |
| SCHEMBL2952068 | 0.70 | MEN1 (0.68) | KDM4EALDH1A1SLC6A4SLC6A3MAPT | |
| SCHEMBL4486670 | 0.69 | KDM4E (0.57) | KDM4EALDH1A1GAASLC6A4SLC6A3 | |
| SCHEMBL184208 | 0.69 | KDM4E (0.61) | KDM4EALDH1A1GAASLC6A4SLC6A3 | |
| SCHEMBL1254366 | 0.69 | NR4A2 (0.54) | KDM4EALDH1A1HSD17B10GAAALOX15 | |
| SCHEMBL28835928 | 0.68 | SLC6A4 (0.50) | KDM4ESLC6A4SLC6A3IKBKBMAPT | |
| SCHEMBL19064093 | 0.68 | KDR (0.44) | KDM4EALDH1A1HSD17B10MAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3400228-A1 | FUSED QUADRACYCLIC COMPOUNDS, COMPOSITIONS AND USES THEREOF | Tabomedex Biosciences, LLC (US) | 2018-11-14 | — | — | EP | disclosed |
| WO-2017120164-A1 | FUSED QUADRACYCLIC COMPOUNDS, COMPOSITIONS AND USES THEREOF | Tabomedex Biosciences, LLC (US) | 2017-07-13 | — | — | WO | disclosed |