Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 1/20 | 0.44 |
| ▸ | RXRB | P28702 | 1/20 | 0.44 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | IGF1R | P08069 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | RARB | P10826 | 6/20 | 0.40 |
| ▸ | CNR2 | P34972 | 3/20 | 0.40 |
| ▸ | CNR1 | P21554 | 2/20 | 0.40 |
| ▸ | PPARA | Q07869 | 1/20 | 0.39 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.39 |
| ▸ | CHRNA10 | Q9GZZ6 | 2/20 | 0.39 |
| ▸ | CHRNA9 | Q9UGM1 | 2/20 | 0.39 |
| ▸ | LTA4H | P09960 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.39 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3535251 | 0.83 | CA2 (0.54) | CYP4A11CA2RARBPPARALTA4H | |
| SCHEMBL19116667 | 0.81 | CA2 (0.50) | CYP4A11CA2IGF1RALOX15RARB | |
| SCHEMBL17194981 | 0.81 | IGF1R (0.42) | RXRARXRBCYP4A11CA2IGF1R | |
| SCHEMBL80441 | 0.79 | IGF1R (0.55) | CYP4A11CA2IGF1RALOX15PPARA | |
| SCHEMBL80615 | 0.79 | TNKS2 (0.47) | CYP4A11CA2IGF1RALOX15CNR2 | |
| SCHEMBL17072086 | 0.78 | ESR1 (0.56) | CA2IGF1RALOX15LTA4HEPHX2 | |
| SCHEMBL17072098 | 0.78 | ESR1 (0.56) | CA2IGF1RALOX15LTA4HEPHX2 | |
| SCHEMBL17072102 | 0.78 | ABL1 (0.46) | CYP4A11CA2IGF1RALOX15LTA4H | |
| SCHEMBL11894717 | 0.78 | RARB (0.52) | CYP4A11CA2RARB | |
| SCHEMBL7140170 | 0.78 | GFER (0.54) | CYP4A11CA2LTA4HEPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3400071-A1 | NOVEL COMPOUNDS WHICH ACTIVATE ESTROGEN RECEPTORS AND COMPOSITIONS AND METHODS OF USING THE SAME | The Board of Trustees of the University of Illinois (US) | 2018-11-14 | — | — | EP | disclosed |
| WO-2017120507-A1 | NOVEL COMPOUNDS WHICH ACTIVATE ESTROGEN RECEPTORS AND COMPOSITIONS AND METHODS OF USING THE SAME | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2017-07-13 | — | — | WO | disclosed |