SCHEMBL19101771

SCHEMBL19101771

CC(=O)Nc1ncnn2c([C@@H]3O[C@](C#N)(CO)[C@H]4OC(C)(C)O[C@@H]34)cc(F)c12

nearest known ligand 0.32

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ EGLN2 Q96KS0 4/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19101821 0.90 — —
SCHEMBL19101802 0.85 TMPRSS2 (0.38) —
SCHEMBL16701322 0.78 — —
SCHEMBL23803200 0.78 TMPRSS2 (0.38) —
SCHEMBL25386594 0.75 TMPRSS2 (0.34) —
SCHEMBL19101835 0.74 TMPRSS2 (0.35) EGLN2
SCHEMBL26823411 0.74 TMPRSS2 (0.35) —
SCHEMBL19101840 0.72 POLRMT (0.36) —
SCHEMBL25244021 0.72 POLRMT (0.36) —
SCHEMBL25389634 0.68 TMPRSS2 (0.33) —

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9701682-B2 Pyrrolo[1,2-f][1,2,4]triazines useful for treating respiratory syncitial virus infections GILEAD SCIENCES, INC. (US) 2017-07-11 — — US disclosed
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