SCHEMBL19101840

SCHEMBL19101840

CC1(C)O[C@H]2[C@H](c3ccc4c(N)ncnn34)O[C@](C#N)(CO)[C@H]2O1

nearest known ligand 0.41

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
▸ POLRMT O00411 1/20 0.36
▸ PI4KA P42356 1/20 0.31
▸ PI4K2B Q8TCG2 1/20 0.31
▸ PI4K2A Q9BTU6 1/20 0.31
▸ PI4KB Q9UBF8 1/20 0.31
▸ PIK3CD O00329 2/20 0.31
▸ MAP4K4 O95819 1/20 0.31
▸ TNK2 Q07912 1/20 0.30
▸ DOT1L Q8TEK3 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25244021 1.00 POLRMT (0.36) POLRMTPI4KAPI4K2BPI4K2API4KB
SCHEMBL25763012 0.91 POLRMT (0.34) POLRMTPIK3CDMAP4K4
SCHEMBL25077335 0.87 POLRMT (0.38) POLRMTPI4KAPI4K2BPI4K2API4KB
SCHEMBL25388205 0.87 POLRMT (0.38) POLRMTPIK3CDDOT1L
SCHEMBL31216422 0.86 POLRMT (0.32) POLRMT
SCHEMBL26277066 0.86 POLRMT (0.35) POLRMTPIK3CDMAP4K4
SCHEMBL25387871 0.85 POLRMT (0.37) POLRMT
SCHEMBL25391944 0.85 POLRMT (0.37) POLRMTDOT1L
SCHEMBL25387226 0.85 POLRMT (0.37) POLRMT
SCHEMBL19779082 0.85 POLRMT (0.34) POLRMT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260109724-A1 ANTIVIRAL COMPOUNDS GILEAD SCIENCES INC (US) 2026-04-23 — — US disclosed
EP-4665737-A1 PHOSPHOLIPID COMPOUNDS AND METHODS OF MAKING AND USING THE SAME GILEAD SCIENCES, INC. (US) 2025-12-24 — — EP disclosed
EP-4107164-B1 ANTIVIRAL COMPOUNDS GILEAD SCIENCES INC (US) 2025-12-03 — — EP disclosed
US-12264173-B2 Antiviral compounds GILEAD SCIENCES, INC. (US) 2025-04-01 — — US disclosed
US-20250090537-A1 ANTIVIRAL COMPOUNDS AND METHODS OF MAKING AND USING THE SAME GILEAD SCIENCES, INC. 2025-03-20 — — US disclosed
US-20250084088-A1 ANTIVIRAL COMPOUNDS AND METHODS OF MAKING AND USING THE SAME GILEAD SCIENCES, INC. 2025-03-13 — — US disclosed
WO-2025049493-A1 ANTIVIRAL COMPOUNDS AND METHODS OF MAKING AND USING THE SAME GILEAD SCIENCES, INC. (US) 2025-03-06 — — WO disclosed
WO-2025049699-A1 ANTIVIRAL COMPOUNDS AND METHODS OF MAKING AND USING THE SAME GILEAD SCIENCES, INC. (US) 2025-03-06 — — WO disclosed
CN-115175735-B Antiviral compounds 吉利德科学公司 2025-03-04 — — CN disclosed
US-20250034186-A1 ANTIVIRAL COMPOUNDS GILEAD SCIENCES, INC. 2025-01-30 — — US disclosed
US-20230212199-A1 PHOSPHOLIPID COMPOUNDS AND METHODS OF MAKING AND USING THE SAME GILEAD SCIENCES, INC. 2023-07-06 — — US disclosed
US-20230212199-A1 PHOSPHOLIPID COMPOUNDS AND METHODS OF MAKING AND USING THE SAME GILEAD SCIENCES, INC. 2023-07-06 — — US disclosed
WO-2023023527-A1 PHOSPHOLIPID COMPOUNDS AND METHODS OF MAKING AND USING THE SAME GILEAD SCIENCES, INC. (US) 2023-02-23 — — WO disclosed
EP-4106877-A1 ANTIVIRAL COMPOUNDS GILEAD SCIENCES, INC. (US) 2022-12-28 — — EP disclosed
EP-4107164-A1 ANTIVIRAL COMPOUNDS GILEAD SCIENCES, INC. (US) 2022-12-28 — — EP disclosed
US-20220356196-A1 ANTIVIRAL COMPOUNDS GILEAD SCIENCES, INC. 2022-11-10 — — US disclosed
US-20210284670-A1 ANTIVIRAL COMPOUNDS GILEAD SCIENCES, INC. 2021-09-16 — — US disclosed
US-20210284669-A1 ANTIVIRAL COMPOUNDS GILEAD SCIENCES, INC. 2021-09-16 — — US disclosed
US-20210284669-A1 ANTIVIRAL COMPOUNDS GILEAD SCIENCES, INC. 2021-09-16 — — US disclosed
US-9701682-B2 Pyrrolo[1,2-f][1,2,4]triazines useful for treating respiratory syncitial virus infections GILEAD SCIENCES, INC. (US) 2017-07-11 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220356196-A1 ANTIVIRAL COMPOUNDS MAVS, HAVCR2, ZC3HAV1 POLRMT 535/4885PI4KA 3421/4885PI4K2B 4161/4885
US-20250090537-A1 ANTIVIRAL COMPOUNDS AND METHODS OF MAKING AND USING THE SAME EIF2AK2, MAVS, ZC3HAV1 POLRMT 13/4885PI4KA 1987/4885PI4K2B 2880/4885
US-20260109724-A1 ANTIVIRAL COMPOUNDS IRF3, IFNAR1, HAVCR2 POLRMT 1073/4885PI4KA 3443/4885PI4K2B 3673/4885
US-20210284670-A1 ANTIVIRAL COMPOUNDS MAVS, HAVCR2, ZC3HAV1 POLRMT 535/4885PI4KA 3421/4885PI4K2B 4161/4885
US-12264173-B2 Antiviral compounds MAVS, HAVCR2, ZC3HAV1 POLRMT 535/4885PI4KA 3421/4885PI4K2B 4161/4885
US-20210284669-A1 ANTIVIRAL COMPOUNDS MAVS, HAVCR2, SNRPA POLRMT 352/4885PI4KA 3878/4885PI4K2B 4369/4885
US-20230212199-A1 PHOSPHOLIPID COMPOUNDS AND METHODS OF MAKING AND USING THE SAME PHOSPHO1, SGMS1, SGMS2 POLRMT 266/4885PI4KA 268/4885PI4K2B 436/4885
US-20250034186-A1 ANTIVIRAL COMPOUNDS MAVS, HAVCR2, SNRPA POLRMT 259/4885PI4KA 3746/4885PI4K2B 4247/4885
US-20250084088-A1 ANTIVIRAL COMPOUNDS AND METHODS OF MAKING AND USING THE SAME EIF2AK2, MAVS, ZC3HAV1 POLRMT 13/4885PI4KA 1987/4885PI4K2B 2880/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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