Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TMPRSS2 | O15393 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23803200 | 0.93 | TMPRSS2 (0.38) | TMPRSS2 | |
| SCHEMBL25386594 | 0.90 | TMPRSS2 (0.34) | TMPRSS2 | |
| SCHEMBL19101835 | 0.89 | TMPRSS2 (0.35) | TMPRSS2 | |
| SCHEMBL26823411 | 0.88 | TMPRSS2 (0.35) | TMPRSS2 | |
| SCHEMBL20943594 | 0.87 | TMPRSS2 (0.33) | TMPRSS2 | |
| SCHEMBL19101821 | 0.85 | — | — | |
| SCHEMBL19101771 | 0.85 | EGLN2 (0.32) | — | |
| SCHEMBL25244021 | 0.84 | POLRMT (0.36) | — | |
| SCHEMBL19101840 | 0.84 | POLRMT (0.36) | — | |
| SCHEMBL25389634 | 0.82 | TMPRSS2 (0.33) | TMPRSS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9701682-B2 | Pyrrolo[1,2-f][1,2,4]triazines useful for treating respiratory syncitial virus infections | GILEAD SCIENCES, INC. (US) | 2017-07-11 | — | — | US | disclosed |