Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.52 |
| ▸ | MGAM | O43451 | 1/20 | 0.52 |
| ▸ | SI | P14410 | 1/20 | 0.52 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | CA12 | O43570 | 3/20 | 0.47 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | LTA4H | P09960 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4464939 | 0.93 | GAA (0.59) | GAAMGAMSIMGAM2CYP1A2 | |
| Hydrochloric Acid SCHEMBL11851530 | 0.91 | GAA (0.56) | GAAMGAMSIMGAM2CYP1A2 | |
| SCHEMBL13756031 | 0.91 | GAA (0.56) | GAAMGAMSIMGAM2CYP1A2 | |
| SCHEMBL4335291 | 0.88 | ALDH1A1 (0.50) | GAAMGAMSIMGAM2TSHR | |
| SCHEMBL20937509 | 0.87 | LTA4H (0.52) | GAAMGAMSIMGAM2CYP1A2 | |
| SCHEMBL8851605 | 0.87 | GAA (0.52) | GAAMGAMSIMGAM2CYP1A2 | |
| SCHEMBL1981808 | 0.86 | TSHR (0.68) | GAAMGAMSIMGAM2TSHR | |
| SCHEMBL72889 | 0.86 | TSHR (0.67) | GAAMGAMSIMGAM2TSHR | |
| SCHEMBL13435480 | 0.86 | GAA (0.46) | GAAMGAMSIMGAM2TSHR | |
| Hydrochloric Acid SCHEMBL1274072 | 0.85 | LTA4H (0.54) | GAAMGAMSIMGAM2CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9700627-B2 | Biodegradable poly (beta-amino esters) and uses thereof | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2017-07-11 | — | — | US | disclosed |