SCHEMBL19105247

SCHEMBL19105247

C#COC(=O)C(CCC)C(=O)OC#C

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HDAC1 Q13547 2/20 0.34
HDAC2 Q92769 2/20 0.34
CHRM1 P11229 1/20 0.34
AKR1A1 P14550 1/20 0.34
CHRM3 P20309 1/20 0.34
HTR2A P28223 1/20 0.34
HTR2C P28335 1/20 0.34
ADRA1A P35348 1/20 0.34
HRH1 P35367 1/20 0.34
DRD3 P35462 1/20 0.34
SLC6A3 Q01959 1/20 0.34
TDP1 Q9NUW8 1/20 0.34
CYP3A4 P08684 2/20 0.33
TSHR P16473 2/20 0.33
NFKB1 P19838 2/20 0.33
NPSR1 Q6W5P4 2/20 0.33
CA1 P00915 1/20 0.31
CA2 P00918 1/20 0.31
HDAC7 Q8WUI4 2/20 0.31
HDAC8 Q9BY41 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19105280 0.88 CA2 (0.41) TDP1CYP3A4TSHRCA1CA2
SCHEMBL10885793 0.83 HDAC1 (0.44) HDAC1HDAC2CHRM1AKR1A1CHRM3
SCHEMBL19105221 0.82 ALDH1A1 (0.31)
SCHEMBL19105446 0.78 METAP1 (0.33) HDAC1HDAC2CHRM1AKR1A1CHRM3
SCHEMBL19105291 0.77 L3MBTL1 (0.37) HDAC1HDAC2CHRM1AKR1A1CHRM3
SCHEMBL19105372 0.75 SLC1A2 (0.35) TSHR
SCHEMBL19105334 0.74 ALDH1A1 (0.37) TDP1
SCHEMBL19105248 0.74 MEN1 (0.37) HDAC1HDAC2CHRM1AKR1A1CHRM3
SCHEMBL19105380 0.74 GAA (0.41) CHRM1TDP1CYP3A4TSHRCA1
SCHEMBL19105346 0.73 GRIK1 (0.32)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170200976-A1 NON-AQUEOUS ELECTROLYTIC SOLUTION AND NON-AQUEOUS ELECTROLYTE SECONDARY BATTERY USING THE SAME MITSUBISHI CHEMICAL CORPORATION (JP) 2017-07-13 US disclosed
US-20170200976-A1 NON-AQUEOUS ELECTROLYTIC SOLUTION AND NON-AQUEOUS ELECTROLYTE SECONDARY BATTERY USING THE SAME MITSUBISHI CHEMICAL CORPORATION (JP) 2017-07-13 US disclosed