Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | HTR7 | P34969 | 2/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 2/20 | 0.39 |
| ▸ | HTR2B | P41595 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.39 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.39 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.38 |
| ▸ | DBH | P09172 | 1/20 | 0.38 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19110586 | 0.86 | SLC2A1 (0.48) | HTR7 | |
| SCHEMBL19110591 | 0.86 | HTR7 (0.54) | HTR7HTR1AHTR2AHTR2CHTR2B | |
| SCHEMBL17317710 | 0.83 | GRIA2 (0.45) | ALDH1A1SMN1; SMN2HTR7HTR1AHTR2A | |
| Hydrochloric Acid SCHEMBL19097284 | 0.82 | GRIA2 (0.44) | ALDH1A1SMN1; SMN2HTR7HTR1AHTR2A | |
| SCHEMBL19110655 | 0.82 | HTR7 (0.43) | HTR7HTR1AHTR2AHTR2CHTR2B | |
| SCHEMBL19110600 | 0.81 | HTR7 (0.43) | ALDH1A1SMN1; SMN2HTR7HTR1AHTR2A | |
| SCHEMBL19110587 | 0.80 | HTR7 (0.53) | SMN1; SMN2HTR7HTR1AHTR2AHTR2C | |
| SCHEMBL19110602 | 0.79 | CYP1A2 (0.40) | ALDH1A1HTR7HTR1AHTR2AHTR2C | |
| SCHEMBL19110592 | 0.76 | HTR7 (0.41) | HTR7HTR1AHTR2AHTR2CHTR2B | |
| SCHEMBL19110593 | 0.75 | HTR7 (0.39) | HTR7HTR1AHTR2AGRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170197960-A1 | ATX MODULATING AGENTS | BIOGEN MA INC. | 2017-07-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170197960-A1 | ATX MODULATING AGENTS | ENPP2, ATXN10, ATXN2 | ALDH1A1 4081/4885SMN1; SMN2 119/4885HTR7 755/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.