Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.45 |
| ▸ | NQO2 | P16083 | 5/20 | 0.39 |
| ▸ | MEN1 | O00255 | 5/20 | 0.35 |
| ▸ | NPC1 | O15118 | 5/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.35 |
| ▸ | RAB9A | P51151 | 4/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | THRA | P10827 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.33 |
| ▸ | USP2 | O75604 | 2/20 | 0.33 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.32 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22951467 | 0.94 | NQO2 (0.48) | ESR1NQO2MEN1NPC1KMT2A | |
| SCHEMBL24604651 | 0.90 | TDP1 (0.42) | ESR1NQO2MEN1NPC1KMT2A | |
| SCHEMBL9968624 | 0.79 | ESR1 (0.42) | ESR1MEN1NPC1KMT2ARAB9A | |
| SCHEMBL23896788 | 0.79 | ESR1 (0.35) | ESR1NPC1RAB9ASMN1; SMN2USP2 | |
| SCHEMBL10202929 | 0.78 | KCNJ1 (0.49) | ESR1KDM4ESMN1; SMN2ALDH1A1L3MBTL1 | |
| SCHEMBL12595077 | 0.78 | PTPN11 (0.48) | ESR1MEN1KMT2AKDM4ESMN1; SMN2 | |
| SCHEMBL22951475 | 0.77 | ALDH1A1 (0.52) | ESR1NQO2MEN1KMT2AKDM4E | |
| SCHEMBL22951223 | 0.77 | HTR3A (0.53) | ESR1NQO2MEN1KMT2AKDM4E | |
| SCHEMBL24634739 | 0.76 | ESR1 (0.39) | ESR1THRATHRB | |
| SCHEMBL19170649 | 0.76 | ESR1 (0.39) | ESR1THRATHRBPSMB5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9931379-B2 | Oxyntomodulin analogs and methods of making and using same | THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (US) | 2018-04-03 | — | — | US | disclosed |
| US-9931379-B2 | Oxyntomodulin analogs and methods of making and using same | THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (US) | 2018-04-03 | — | — | US | disclosed |
| US-20170196940-A1 | OXYNTOMODULIN ANALOGS AND METHODS OF MAKING AND USING SAME | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2017-07-13 | — | — | US | disclosed |
| US-20170196940-A1 | OXYNTOMODULIN ANALOGS AND METHODS OF MAKING AND USING SAME | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2017-07-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170196940-A1 | OXYNTOMODULIN ANALOGS AND METHODS OF MAKING AND USING SAME | PTMS, OGFRL1, SHBG | ESR1 3091/4885NQO2 4120/4885MEN1 2444/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.