Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 2/20 | 0.56 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.49 |
| ▸ | PPARG | P37231 | 7/20 | 0.47 |
| ▸ | PPARA | Q07869 | 7/20 | 0.47 |
| ▸ | SRD5A2 | P31213 | 3/20 | 0.44 |
| ▸ | PPARD | Q03181 | 2/20 | 0.43 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.42 |
| ▸ | BAX | Q07812 | 1/20 | 0.42 |
| ▸ | MMP12 | P39900 | 1/20 | 0.42 |
| ▸ | MMP13 | P45452 | 1/20 | 0.42 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.42 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.42 |
| ▸ | ACACB | O00763 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28264926 | 0.83 | TRPA1 (0.52) | — | |
| SCHEMBL6869166 | 0.80 | LTA4H (0.57) | LTA4HFFAR1PPARGPPARASRD5A2 | |
| SCHEMBL6869622 | 0.80 | SRR (0.45) | FFAR1PPARGPPARAMMP12MMP13 | |
| SCHEMBL12379287 | 0.79 | LTA4H (0.60) | LTA4HFFAR1PPARGPPARASRD5A2 | |
| SCHEMBL12379282 | 0.79 | LTA4H (0.60) | LTA4HFFAR1PPARGPPARASRD5A2 | |
| SCHEMBL19112060 | 0.77 | LTA4H (0.53) | LTA4HFFAR1PPARGPPARAPPARD | |
| Hydrochloric Acid SCHEMBL6479293 | 0.77 | LTA4H (0.58) | LTA4HFFAR1PPARGPPARAPPARD | |
| Hydrochloric Acid SCHEMBL6479299 | 0.77 | LTA4H (0.58) | LTA4HFFAR1PPARGPPARAPPARD | |
| SCHEMBL11434236 | 0.77 | LTA4H (0.58) | LTA4HFFAR1PPARGPPARAPPARD | |
| Hydrochloric Acid SCHEMBL2296279 | 0.77 | LTA4H (0.58) | LTA4HFFAR1PPARGPPARAPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2470514-B1 | PSEUDO-DIPEPTIDES AS MMP INHIBITORS | COMMISSARIAT L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES (FR) | 2017-07-12 | — | — | EP | disclosed |