Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRS3 | P32247 | 1/20 | 0.39 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.39 |
| ▸ | KDM1A | O60341 | 2/20 | 0.38 |
| ▸ | DGAT1 | O75907 | 4/20 | 0.36 |
| ▸ | CSF1R | P07333 | 2/20 | 0.33 |
| ▸ | FASN | P49327 | 1/20 | 0.32 |
| ▸ | CCR5 | P51681 | 3/20 | 0.32 |
| ▸ | DAO | P14920 | 2/20 | 0.32 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.31 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | HTR2C | P28335 | 1/20 | 0.31 |
| ▸ | HTR2B | P41595 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19521677 | 0.95 | NPY5R (0.44) | BRS3NPY5RKDM1ADGAT1CSF1R | |
| SCHEMBL19117165 | 0.92 | KDM1A (0.35) | BRS3NPY5RKDM1ACCR5DAO | |
| SCHEMBL19521578 | 0.82 | IDO1 (0.33) | BRS3KDM1A | |
| SCHEMBL19521676 | 0.79 | CCR5 (0.33) | BRS3CCR5 | |
| SCHEMBL19087011 | 0.75 | NPY5R (0.41) | BRS3NPY5RKDM1ADGAT1CSF1R | |
| SCHEMBL19077858 | 0.74 | NPY5R (0.39) | BRS3NPY5RKDM1ADGAT1CSF1R | |
| SCHEMBL28576254 | 0.73 | BRS3 (0.35) | BRS3NPY5RKDM1ADAO | |
| SCHEMBL24486069 | 0.71 | NPY5R (0.37) | BRS3NPY5RKDM1ADGAT1CSF1R | |
| SCHEMBL17571952 | 0.71 | NPY5R (0.45) | BRS3NPY5RKDM1ADGAT1CSF1R | |
| SCHEMBL19077894 | 0.70 | NPY5R (0.42) | BRS3NPY5RKDM1ADGAT1CSF1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017120194-A1 | PYRIDINE AND PYRIDIMINE COMPOUNDS AS PI3K-GAMMA INHIBITORS | INCYTE CORPORATION (US) | 2017-07-13 | — | — | WO | disclosed |