SCHEMBL191235

SCHEMBL191235

CC(C)(C)[Si](C)(C)OCC[C@H](N)C(=O)O

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NOS3 P29474 1/20 0.41
NOS1 P29475 1/20 0.41
NOS2 P35228 1/20 0.41
ALDH1A1 P00352 1/20 0.40
SLC1A2 P43004 4/20 0.40
SLC1A1 P43005 4/20 0.40
SLC1A3 P43003 3/20 0.40
GRIK1 P39086 4/20 0.39
GRIK2 Q13002 4/20 0.39
GSR P00390 2/20 0.39
SLC7A5 Q01650 1/20 0.39
GRM8 O00222 1/20 0.39
GRM6 O15303 1/20 0.39
GRIN2D O15399 1/20 0.39
GRIN3B O60391 1/20 0.39
CYP1A2 P05177 1/20 0.39
GRM5 P41594 1/20 0.39
GRIA1 P42261 1/20 0.39
GRIA2 P42262 1/20 0.39
GRIA3 P42263 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL191236 1.00 NOS3 (0.41) NOS3NOS1NOS2ALDH1A1SLC1A2
SCHEMBL490891 1.00 NOS3 (0.41) NOS3NOS1NOS2ALDH1A1SLC1A2
SCHEMBL28580283 0.90 GSR (0.43) NOS3NOS1NOS2ALDH1A1GSR
SCHEMBL13639864 0.84 SLC1A1 (0.55) SLC1A2SLC1A1SLC1A3GRIK1GRIK2
SCHEMBL19699429 0.83 IDO1 (0.34) SLC1A1
SCHEMBL1067509 0.83 IDO1 (0.34) SLC1A1
SCHEMBL1067514 0.83 IDO1 (0.34) SLC1A1
SCHEMBL30980082 0.83 IDO1 (0.34) SLC1A1
SCHEMBL10314812 0.81 NOS3 (0.38) NOS3NOS1NOS2ALDH1A1SLC1A2
SCHEMBL20591675 0.81 NOS3 (0.38) NOS3NOS1NOS2ALDH1A1SLC1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 211 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210329924-A1 METAL-BASED ANTIMICROBIAL COMPOSITION AND METHOD OF USING APEX BIOMATERIALS INC. (CA) 2021-10-28 US claimed
US-20190177169-A1 MODIFIED GRAPHITE INTERCALATED COMPOUNDS AND METHODS OF MAKING AND USING THEM MEGAMATTER, INC. (US) 2019-06-13 US claimed
EP-3468914-A1 MODIFIED GRAPHITE INTERCALATED COMPOUNDS AND METHODS OF MAKING AND USING THEM Megamatter Inc. (US) 2019-04-17 EP claimed
WO-2017218547-A1 MODIFIED GRAPHITE INTERCALATED COMPOUNDS AND METHODS OF MAKING AND USING THEM MEGAMATTER, INC. (US) 2017-12-21 WO claimed
US-8998518-B2 Dual cleaning apparatus MUHR-SWEENEY AUDREY (US) 2015-04-07 US claimed
US-20140110263-A1 Superhydrophobic Anodized Metals and Method of Making Same U.S. DEPARTMENT OF ENERGY 2014-04-24 US claimed
US-20130327357-A1 DUAL CLEANING APPARATUS MUHR-SWEENEY AUDREY (US) 2013-12-12 US claimed
US-8534945-B2 Dual cleaning apparatus MUHR-SWEENEY AUDREY (US) 2013-09-17 US claimed
US-20120207530-A1 DUAL CLEANING APPARATUS MUHR-SWEENEY AUDREY (US) 2012-08-16 US claimed
US-7553100-B2 Dual cleaning apparatus MUHR-SWEENEY AUDREY 2009-06-30 US claimed
US-20050147455-A1 Dual cleaning apparatus MUHR-SWEENEY AUDREY (US) 2005-07-07 US claimed
US-20040136770-A1 Dual cleaning apparatus MUHR-SWEENEY AUDREY (US) 2004-07-15 US claimed
US-20260116921-A1 PEPTIDE INHIBITORS OF INTERLEUKIN-23 RECEPTOR AND THEIR USE TO TREAT INFLAMMATORY DISEASES PROTAGONIST THERAPEUTICS INC (US) 2026-04-30 US disclosed
EP-3570864-B1 PEPTIDE INHIBITORS OF INTERLEUKIN-23 RECEPTOR AND THEIR USE TO TREAT INFLAMMATORY DISEASES PROTAGONIST THERAPEUTICS INC (US) 2026-02-18 EP disclosed
US-12552836-B2 Peptide inhibitors of interleukin-23 receptor and their use to treat inflammatory diseases PROTAGONIST THERAPEUTICS, INC. (US) 2026-02-17 US disclosed
EP-4423014-B1 OPTIMIZED METHOD FOR THE PREPARATION AND ISOLATION OF HYDROCYANIC ACID AND METHOD FOR ITS CONVERSION TO METHACRYLIC ACID (MAS) AND / OR ALKYL METHACRYLATE ROEHM GMBH (DE) 2025-12-03 EP disclosed
EP-0322796-A1 Production method of hydrocyanic acid NITTO CHEMICAL INDUSTRY CO., LTD. (JP) 1989-07-05 EP disclosed
EP-0108737-B1 HYDROGEN CYANIDE PROCESS Monsanto Company (US) 1986-05-21 EP disclosed
US-4457904-A Hydrogen cyanide process MONSANTO COMPANY (US) 1984-07-03 US disclosed
EP-0108737-A1 Hydrogen cyanide process Monsanto Company (US) 1984-05-16 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12552836-B2 Peptide inhibitors of interleukin-23 receptor and their use to treat inflammatory diseases IL23R, IL17A, IL36G NOS3 810/4885NOS1 1575/4885NOS2 1919/4885
US-20260116921-A1 PEPTIDE INHIBITORS OF INTERLEUKIN-23 RECEPTOR AND THEIR USE TO TREAT INFLAMMATORY DISEASES IL23R, IL1RN, IL36G NOS3 881/4885NOS1 2111/4885NOS2 2572/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.