Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.59 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | APEX1 | P27695 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 6/20 | 0.32 |
| ▸ | NAAA | Q02083 | 1/20 | 0.31 |
| ▸ | RAD52 | P43351 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3502379 | 1.00 | TSHR (0.59) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL16207850 | 1.00 | TSHR (0.59) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL3503531 | 0.98 | TSHR (0.56) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL64556 | 0.93 | TSHR (0.53) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL5600819 | 0.89 | TSHR (0.49) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL16223339 | 0.88 | TSHR (0.61) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL3503198 | 0.88 | TSHR (0.61) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL16223397 | 0.88 | TSHR (0.61) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL1024054 | 0.88 | TSHR (0.61) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL3503229 | 0.88 | TSHR (0.61) | TSHRPOLBAPEX1HTTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240018358-A1 | POLYSILOXANE-BASED RESIN AND UTILIZATION THEREOF | KANEKA CORPORATION (JP) | 2024-01-18 | — | — | US | disclosed |
| WO-2023119928-A1 | METHOD FOR PRODUCING DISPERSION LIQUID OR SOLUTION IN WHICH WATER CONTAINING POLYSILOXANE-BASED RESIN SERVES AS MEDIUM | 株式会社カネカ | 2023-06-29 | — | — | WO | disclosed |
| EP-3202811-A1 | ACTINIC RADIATION CURABLE COMPOSITION | Kaneka Corporation (JP) | 2017-08-09 | — | — | EP | disclosed |
| US-20170204231-A1 | ACTINIC RADIATION CURABLE COMPOSITION | KANEKA CORPORATION (JP) | 2017-07-20 | — | — | US | disclosed |
| CN-101254924-A | Silicane coupling agent surface grafted modified clay as well as preparation method and use thereof | CHINESE ACAD INST CHEMISTRY (CN) | 2008-09-03 | — | — | CN | disclosed |