SCHEMBL3502379

SCHEMBL3502379

C=C(C)C(=O)OCCCCC[Si](C)(C)OC

nearest known ligand 0.59

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.59
POLB P06746 1/20 0.46
APEX1 P27695 1/20 0.46
HTT P42858 1/20 0.46
TDP1 Q9NUW8 1/20 0.46
THRB P10828 1/20 0.43
ALDH1A1 P00352 3/20 0.38
CYP3A4 P08684 1/20 0.32
ACHE P22303 6/20 0.32
NAAA Q02083 1/20 0.31
RAD52 P43351 1/20 0.30
NPSR1 Q6W5P4 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19124382 1.00 TSHR (0.59) TSHRPOLBAPEX1HTTTDP1
SCHEMBL16207850 1.00 TSHR (0.59) TSHRPOLBAPEX1HTTTDP1
SCHEMBL3503531 0.98 TSHR (0.56) TSHRPOLBAPEX1HTTTDP1
SCHEMBL64556 0.93 TSHR (0.53) TSHRPOLBAPEX1HTTTDP1
SCHEMBL5600819 0.89 TSHR (0.49) TSHRPOLBAPEX1HTTTDP1
SCHEMBL16223339 0.88 TSHR (0.61) TSHRPOLBAPEX1HTTTDP1
SCHEMBL3503198 0.88 TSHR (0.61) TSHRPOLBAPEX1HTTTDP1
SCHEMBL16223397 0.88 TSHR (0.61) TSHRPOLBAPEX1HTTTDP1
SCHEMBL1024054 0.88 TSHR (0.61) TSHRPOLBAPEX1HTTTDP1
SCHEMBL3503229 0.88 TSHR (0.61) TSHRPOLBAPEX1HTTTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240018358-A1 POLYSILOXANE-BASED RESIN AND UTILIZATION THEREOF KANEKA CORPORATION (JP) 2024-01-18 US disclosed
US-11787891-B2 Modified block copolymer composition ZEON CORPORATION (JP) 2023-10-17 US disclosed
WO-2023119928-A1 METHOD FOR PRODUCING DISPERSION LIQUID OR SOLUTION IN WHICH WATER CONTAINING POLYSILOXANE-BASED RESIN SERVES AS MEDIUM 株式会社カネカ 2023-06-29 WO disclosed
EP-3670554-B1 MODIFIED BLOCK COPOLYMER COMPOSITION ZEON CORP (JP) 2022-01-05 EP disclosed
US-20200255650-A1 MODIFIED BLOCK COPOLYMER COMPOSITION ZEON CORPORATION (JP) 2020-08-13 US disclosed
EP-3670554-A1 MODIFIED BLOCK COPOLYMER COMPOSITION Zeon Corporation (JP) 2020-06-24 EP disclosed
EP-3202811-A1 ACTINIC RADIATION CURABLE COMPOSITION Kaneka Corporation (JP) 2017-08-09 EP disclosed
US-20170204231-A1 ACTINIC RADIATION CURABLE COMPOSITION KANEKA CORPORATION (JP) 2017-07-20 US disclosed
US-20170073547-A1 Curable Composition, Temporary Bonding Material, and Method for Temporarily Bonding Component Part and Substrate By Same CENTRAL GLASS COMPANY, LTD. (JP) 2017-03-16 US disclosed
US-20170073547-A1 Curable Composition, Temporary Bonding Material, and Method for Temporarily Bonding Component Part and Substrate By Same CENTRAL GLASS COMPANY, LTD. (JP) 2017-03-16 US disclosed
US-9266981-B2 Conjugated diene random copolymer having alkoxysilane unit KOREA KUMHO PETROCHEMICAL CO., LTD. (KR) 2016-02-23 US disclosed
US-20150191607-A1 Anti-fouling Paints and Coatings REACTIVE SURFACES, LTD (US) 2015-07-09 US disclosed
US-20150065639-A1 CONJUGATED DIENE RANDOM COPOLYMER HAVING ALKOXYSILANE UNIT KOREA KUMHO PETROCHEMICAL CO., LTD. (KR) 2015-03-05 US disclosed
US-20100210745-A1 Molecular Healing of Polymeric Materials, Coatings, Plastics, Elastomers, Composites, Laminates, Adhesives, and Sealants by Active Enzymes REACTIVE SURFACES, LTD. (US) 2010-08-19 US disclosed
US-4957808-A POROUS SUPPROT LAMINATED WITH PLASTIC FILM RICOH COMPANY, LTD. (JP) 1990-09-18 US disclosed